Genomic Insights for Personalized Care: Motivating At-Risk Individuals Toward Evidence-Based Health Practices
Background Lung cancer and tobacco use pose significant global health challenges,
necessitating a comprehensive translational roadmap for improved prevention strategies …
necessitating a comprehensive translational roadmap for improved prevention strategies …
Stratifying Lung Adenocarcinoma Risk with Multi-ancestry Polygenic Risk Scores in East Asian Never-Smokers
B Blechter, X Wang, J Shi, K Shiraishi, J Choi… - medRxiv, 2024 - medrxiv.org
Background Lung adenocarcinoma (LUAD) among never-smokers is a public health burden
especially prevalent in East Asian (EAS) women. Polygenic risk scores (PRSs), which …
especially prevalent in East Asian (EAS) women. Polygenic risk scores (PRSs), which …
Analysis-ready VCF at Biobank scale using Zarr
EA Czech, TR Millar, TE White, B Jeffery, A Miles… - bioRxiv, 2024 - biorxiv.org
Background: Variant Call Format (VCF) is the standard file format for interchanging genetic
variation data and associated quality control metrics. The usual row-wise encoding of the …
variation data and associated quality control metrics. The usual row-wise encoding of the …