Epithelial–mesenchymal transition (EMT) is an essential process in normal embryonic
development and tissue regeneration. However, aberrant reactivation of EMT is associated …

Simple Summary Vimentin is an important filamentous protein providing structural and
functional support to the cell. During initial stages of cancer development, vimentin …

Epithelial‐mesenchymal transition (EMT) is a complex process with a primordial role in
cellular transformation whereby an epithelial cell transforms and acquires a mesenchymal …

Epithelial‐to‐mesenchymal transition (EMT) is implicated in a wide array of malignant
behaviors of cancers, including proliferation, invasion, and metastasis. Most notably, previou …

Epithelial-to-mesenchymal transition (EMT) mechanism is responsible for metastasis and
migration of cancer cells to neighboring cells and tissues. Morphologically, epithelial cells …

Therapy resistance is a characteristic of cancer cells that significantly reduces the
effectiveness of drugs. Despite the popularity of cisplatin (CP) as a chemotherapeutic agent …

WNT-signaling controls important cellular processes throughout embryonic development
and adult life, so any deregulation of this signaling can result in a wide range of pathologies …

Transforming growth factor-β (TGF-β) signaling shows important roles in both physiology
and pathology, especially in the progression of inflammatory diseases including cancer …

Simple Summary The epithelial to mesenchymal transition (EMT) is a well-documented
process in the study of cancer metastases. The cytoskeleton is an intricate network involved …

Dealing with cancer is of importance due to enhanced incidence rate of this life-threatening
disorder. Chemotherapy is an ideal candidate in overcoming and eradication of cancer. To …