Even in the modern era of precision medicine and immunotherapy, chemotherapy with
platinum (Pt) drugs remains among the most commonly prescribed medications against a …

The search for better chemotherapeutic drugs to alleviate the deficiencies of existing
platinum (Pt) drugs has picked up the pace in the millennium. There has been a disparate …

The presence of the G-quadruplex (G4) structure in the promoter region of the human bcl-2
oncogenes makes it a promising target for developing anti-cancer therapeutics. Bcl-2 …

Cancer poses a significant threat to global health and new treatments are required to
improve the prognosis for patients. Previously, unconventional platinum complexes …

Simple Summary Traditional intravenous platinum (II) chemotherapy drugs such as cisplatin,
oxaliplatin and carboplatin are highly effective in treating multiple cancer types …

Targeting of G-quadruplex (GQ) nucleic acids, which are helical four-stranded structures
formed from guanine-rich nucleic acid sequences, has emerged in recent years as an …

Cyclometalated 1, 3-bis (8-quinolyl) phenyl chloroplatinum (II)(Pt1) shows selective
luminescence transduction of G-quadruplex binding over duplex DNA. The effect is …