During the past 30 yr, investigating the physiology of eating behaviors has generated a truly
vast literature. This is fueled in part by a dramatic increase in obesity and its comorbidities …

Hypocretin/orexin neurons are distributed restrictively in the hypothalamus, a brain region
known to orchestrate diverse functions including sleep, reward processing, food intake …

Animals continuously weigh hunger and thirst against competing needs, such as social
contact and mating, according to state and opportunity. Yet neuronal mechanisms of sensing …

Fast-acting neurotransmitters and slow, modulatory neuropeptides are co-released from
neurons in the central nervous system, albeit from distinct synaptic vesicles. The …

The lateral hypothalamic area (LHA) is a subcortical brain region that exerts control over
motivated behavior, feeding, and energy balance across species. Recent single-cell …

Assigning behavioral roles to genetically defined neurons within the lateral hypothalamus
(LH) is an ongoing challenge. We demonstrate that a subpopulation of LH GABAergic …

The hypothalamus is an evolutionarily conserved endocrine interface that, among other
roles, links central homeostatic control to adaptive bodily responses by releasing hormones …

The neurotensin system spans across the central nervous system, to the enteric nervous
system (gut), and the periphery to govern behaviors and physiological responses that tune …

Determining the spatial organization and morphological characteristics of molecularly
defined cell types is a major bottleneck for characterizing the architecture underpinning …

Cortical layer 6b is considered by many to be a remnant of the subplate that forms during
early stages of neocortical development, but its role in the adult is not well understood. Its …