Photodynamic therapy review: principles, photosensitizers, applications, and future directions

JH Correia, JA Rodrigues, S Pimenta, T Dong, Z Yang - Pharmaceutics, 2021 - mdpi.com
Photodynamic therapy (PDT) is a minimally invasive therapeutic modality that has gained
great attention in the past years as a new therapy for cancer treatment. PDT uses …

Recent advances in radiation therapy and photodynamic therapy

LM Chong, DJH Tng, LLY Tan, MLK Chua… - Applied Physics …, 2021 - pubs.aip.org
In the past 100 years, external beam energy for the treatment of cancer has continually
evolved. Two main modes have been developed. The first is radiotherapy which involves …

A biomineral-inspired approach of synthesizing colloidal persistent phosphors as a multicolor, intravital light source

F Yang, X Wu, H Cui, Z Ou, S Jiang, S Cai, Q Zhou… - Science …, 2022 - science.org
Many in vivo biological techniques, such as fluorescence imaging, photodynamic therapy,
and optogenetics, require light delivery into biological tissues. The limited tissue penetration …

Reactive oxygen species produced by 5-aminolevulinic acid photodynamic therapy in the treatment of cancer

P Pignatelli, S Umme, DL D'Antonio, A Piattelli… - International Journal of …, 2023 - mdpi.com
Cancer is the leading cause of death worldwide and several anticancer therapies take
advantage of the ability of reactive oxygen species to kill cancer cells. Added to this is the …

Metronomic photodynamic therapy using an implantable LED device and orally administered 5-aminolevulinic acid

I Kirino, K Fujita, K Sakanoue, R Sugita, K Yamagishi… - Scientific reports, 2020 - nature.com
Metronomic photodynamic therapy (mPDT) is a form of PDT that induces cancer cell death
by intermittent continuous irradiation with a relatively weak power of light for a long duration …

Cherenkov radiation fluence estimates in tissue for molecular imaging and therapy applications

AK Glaser, R Zhang, JM Andreozzi… - Physics in Medicine …, 2015 - iopscience.iop.org
Cherenkov radiation has recently emerged as an interesting phenomenon for a number of
applications in the biomedical sciences. Its unique properties, including broadband …

Systematic review and meta-analysis of in vitro anti-human cancer experiments investigating the use of 5-aminolevulinic acid (5-ALA) for photodynamic therapy

Y Shinoda, D Kato, R Ando, H Endo, T Takahashi… - Pharmaceuticals, 2021 - mdpi.com
5-Aminolevulinic acid (5-ALA) is an amino acid derivative and a precursor of protoporphyrin
IX (PpIX). The photophysical feature of PpIX is clinically used in photodynamic diagnosis …

Activating Photodynamic Therapy in vitro with Cerenkov Radiation Generated from Yttrium-90

BA Hartl, H Hirschberg, L Marcu… - Journal of …, 2016 - dl.begellhouse.com
The translation of photodynamic therapy (PDT) to the clinical setting has primarily been
limited to easily accessible and/or superficial diseases, for which traditional light delivery …

[HTML][HTML] Versatile nanosystem-based cancer theranostics: design inspiration and predetermined routing

Y Opoku-Damoah, R Wang, J Zhou, Y Ding - Theranostics, 2016 - ncbi.nlm.nih.gov
The relevance of personalized medicine, aimed at a more individualized drug therapy, has
inspired research into nano-based concerted diagnosis and therapeutics (theranostics). As …

Impact of lipid composition and photosensitizer hydrophobicity on the efficiency of light-triggered liposomal release

J Massiot, A Makky, F Di Meo, D Chapron… - Physical Chemistry …, 2017 - pubs.rsc.org
Photo-triggerable liposomes are considered nowadays as promising drug delivery devices
due to their potential to release encapsulated drugs in a spatial and temporal manner. In this …