Immunogenic cell stress and death
Dying mammalian cells emit numerous signals that interact with the host to dictate the
immunological correlates of cellular stress and death. In the absence of reactive antigenic …
immunological correlates of cellular stress and death. In the absence of reactive antigenic …
Viroporins and inflammasomes: a key to understand virus-induced inflammation
Viroporins are virus encoded proteins that alter membrane permeability and can trigger
subsequent cellular signals. Oligomerization of viroporin subunits results in formation of a …
subsequent cellular signals. Oligomerization of viroporin subunits results in formation of a …
A tale of two viruses: immunological insights into HCV/HIV coinfection
ST Gobran, P Ancuta, NH Shoukry - Frontiers in immunology, 2021 - frontiersin.org
Nearly 2.3 million individuals worldwide are coinfected with human immunodeficiency virus
(HIV) and hepatitis C virus (HCV). Odds of HCV infection are six times higher in people living …
(HIV) and hepatitis C virus (HCV). Odds of HCV infection are six times higher in people living …
Signalling, sorting and scaffolding adaptors for Toll-like receptors
Toll-like receptors (TLRs) are danger-sensing receptors that typically propagate self-limiting
inflammatory responses, but can unleash uncontrolled inflammation in non-homeostatic or …
inflammatory responses, but can unleash uncontrolled inflammation in non-homeostatic or …
Decreased expression of the host long-noncoding RNA-GM facilitates viral escape by inhibiting the kinase activity TBK1 via S-glutathionylation
Y Wang, P Wang, Y Zhang, J Xu, Z Li, Z Li, Z Zhou… - Immunity, 2020 - cell.com
Viruses have evolved multiple strategies to evade elimination by the immune system. Here
we examined the contribution of host long noncoding RNAs (lncRNAs) in viral immune …
we examined the contribution of host long noncoding RNAs (lncRNAs) in viral immune …
Research progress on Toll-like receptor signal transduction and its roles in antimicrobial immune responses
P Xia, Y Wu, S Lian, L Yan, X Meng, Q Duan… - Applied Microbiology and …, 2021 - Springer
When microorganisms invade a host, the innate immune system first recognizes the
pathogen-associated molecular patterns of these microorganisms through pattern …
pathogen-associated molecular patterns of these microorganisms through pattern …
Flaviviridae Nonstructural Proteins: The Role in Molecular Mechanisms of Triggering Inflammation
A Latanova, E Starodubova, V Karpov - Viruses, 2022 - mdpi.com
Members of the Flaviviridae family are posing a significant threat to human health
worldwide. Many flaviviruses are capable of inducing severe inflammation in humans …
worldwide. Many flaviviruses are capable of inducing severe inflammation in humans …
TRIM26 is a critical host factor for HCV replication and contributes to host tropism
Hepatitis C virus (HCV) remains a major human pathogen that requires better understanding
of virus-host interactions. In this study, we performed a genome-wide CRISPR-Cas9 …
of virus-host interactions. In this study, we performed a genome-wide CRISPR-Cas9 …
[HTML][HTML] Seneca Valley virus 2C and 3C inhibit type I interferon production by inducing the degradation of RIG-I
W Wen, M Yin, H Zhang, T Liu, H Chen, P Qian, J Hu… - Virology, 2019 - Elsevier
Seneca Valley virus (SVV) is a member of the Picornaviridae family, which has been used to
treat neuroendocrine cancer. The innate immune system plays an important role in SVV …
treat neuroendocrine cancer. The innate immune system plays an important role in SVV …
Hepatitis C virus: evading the intracellular innate immunity
Hepatitis C virus (HCV) infections constitute a major public health problem and are the main
cause of chronic hepatitis and liver disease worldwide. The existing drugs, while effective …
cause of chronic hepatitis and liver disease worldwide. The existing drugs, while effective …