Inflammageing: chronic inflammation in ageing, cardiovascular disease, and frailty
L Ferrucci, E Fabbri - Nature Reviews Cardiology, 2018 - nature.com
Most older individuals develop inflammageing, a condition characterized by elevated levels
of blood inflammatory markers that carries high susceptibility to chronic morbidity, disability …
of blood inflammatory markers that carries high susceptibility to chronic morbidity, disability …
Interleukin‐1 gene polymorphisms and chronic periodontitis in adult whites: a systematic review and meta‐analysis
NY Karimbux, VM Saraiya, S Elangovan… - Journal of …, 2012 - Wiley Online Library
Background: Interleukin‐1 (IL‐1) gene polymorphisms have been associated with increased
levels of inflammatory mediators and several inflammatory diseases. Periodontitis is a …
levels of inflammatory mediators and several inflammatory diseases. Periodontitis is a …
Polymorphisms in the inflammatory pathway genes TLR2, TLR4, TLR9, LY96, NFKBIA, NFKB1, TNFA, TNFRSF1A, IL6R, IL10, IL23R, PTPN22, and PPARG are …
S Bank, P Skytt Andersen, J Burisch, N Pedersen… - PLoS …, 2014 - journals.plos.org
Background The inflammatory bowel diseases (IBD), Crohn's disease (CD) and ulcerative
colitis (UC), result from the combined effects of susceptibility genes and environmental …
colitis (UC), result from the combined effects of susceptibility genes and environmental …
Single nucleotide polymorphisms located in TNFA, IL1RN, IL6R, and IL6 genes are associated with COVID‐19 risk and severity in an Iranian population
Cytokines play pivotal functions in coronavirus disease 2019 (COVID‐19) pathogenesis.
However, little is known about the rationale and importance of genetic variations associated …
However, little is known about the rationale and importance of genetic variations associated …
Pro-inflammatory interleukin-1 genotypes potentiate the risk of coronary artery disease and cardiovascular events mediated by oxidized phospholipids and lipoprotein …
Objectives: The aim of this study was to assess the influence of pro-inflammatory interleukin
(IL)-1 genotype status on the risk for coronary artery disease (CAD), defined as> 50 …
(IL)-1 genotype status on the risk for coronary artery disease (CAD), defined as> 50 …
Interleukin-1 and stroke: biomarker, harbinger of damage, and therapeutic target
A Denes, E Pinteaux, NJ Rothwell… - Cerebrovascular Diseases, 2011 - karger.com
Inflammation is established as a contributor to cerebrovascular disease. Risk factors for
stroke include many conditions associated with chronic or acute inflammation, and …
stroke include many conditions associated with chronic or acute inflammation, and …
Associations between functional polymorphisms in the NFκB signaling pathway and response to anti-TNF treatment in Danish patients with inflammatory bowel …
S Bank, PS Andersen, J Burisch, N Pedersen… - The …, 2014 - nature.com
Antitumor necrosis factor-α (TNF-α) is used for treatment of severe cases of inflammatory
bowel diseases (IBD), including Crohn's disease (CD) and ulcerative colitis (UC). However …
bowel diseases (IBD), including Crohn's disease (CD) and ulcerative colitis (UC). However …
Polymorphisms in the NF kB, TNF‐alpha, IL‐1beta, and IL‐18 pathways are associated with response to anti‐TNF therapy in Danish patients with inflammatory bowel …
S Bank, M Julsgaard, OK Abed… - Alimentary …, 2019 - Wiley Online Library
Background Anti‐tumor necrosis factor‐α (TNF‐α) is used for the treatment of severe cases
of IBD, including Crohn's disease (CD) and ulcerative colitis (UC). However, one‐third of the …
of IBD, including Crohn's disease (CD) and ulcerative colitis (UC). However, one‐third of the …
The Interleukins Orchestrate Mucosal Immune Responses to Salmonella Infection in the Intestine
FC Huang - Cells, 2021 - mdpi.com
Salmonella infection remains one of the major public health problems in the world, with
increasing resistance to antibiotics. The resolution is to explore the pathogenesis of the …
increasing resistance to antibiotics. The resolution is to explore the pathogenesis of the …
Early Treatment and IL1RN Single‐Nucleotide Polymorphisms Affect Response to Anakinra in Systemic Juvenile Idiopathic Arthritis
M Pardeo, MN Rossi, D Pires Marafon… - Arthritis & …, 2021 - Wiley Online Library
Objective To evaluate the impact of early treatment and IL1RN genetic variants on the
response to anakinra in systemic juvenile idiopathic arthritis (JIA). Methods Response to …
response to anakinra in systemic juvenile idiopathic arthritis (JIA). Methods Response to …