Pharmacological effects of cisplatin combination with natural products in cancer chemotherapy
Cisplatin and other platinum-based drugs, such as carboplatin, ormaplatin, and oxaliplatin,
have been widely used to treat a multitude of human cancers. However, a considerable …
have been widely used to treat a multitude of human cancers. However, a considerable …
Ellagic acid: Pharmacological activities and molecular mechanisms involved in liver protection
WR García-Niño, C Zazueta - Pharmacological Research, 2015 - Elsevier
Traditional drugs or therapies rarely have effects on regression of chronic liver diseases,
which result in many cases from sustained oxidative stress. In recent years, ellagic acid (EA) …
which result in many cases from sustained oxidative stress. In recent years, ellagic acid (EA) …
Hesperidin has a protective effect on paclitaxel-induced testicular toxicity through regulating oxidative stress, apoptosis, inflammation and endoplasmic reticulum …
Paclitaxel (PTX) is widely used to treat a number of malignancies, although it has toxic side
effects. Hesperidin (HES) has a wide range of biological and pharmacological properties …
effects. Hesperidin (HES) has a wide range of biological and pharmacological properties …
Carvacrol reduces abnormal and dead sperm counts by attenuating sodium arsenite‐induced oxidative stress, inflammation, apoptosis, and autophagy in the …
Arsenic (As) is a highly toxic metalloid. Carvacrol (CAR) is the active ingredient of
Lamiaceae plants and has various biological and pharmacological properties. The present …
Lamiaceae plants and has various biological and pharmacological properties. The present …
Chrysin protects against testicular toxicity caused by lead acetate in rats with its antioxidant, anti‐inflammatory, and antiapoptotic properties
In the present study, the protective effects of chrysin (CHR) against testicular damage
caused by lead acetate (PbAc) were examined. In this way, 30 min after rats were given 25 …
caused by lead acetate (PbAc) were examined. In this way, 30 min after rats were given 25 …
Protective effect of curcumin in cisplatin-induced oxidative injury in rat testis: mitogen-activated protein kinase and nuclear factor-kappa B signaling pathways
YO Ilbey, E Ozbek, M Cekmen, A Simsek… - Human …, 2009 - academic.oup.com
BACKGROUND The aim of this study was to investigate the cellular/biochemical
mechanisms by which cisplatin (CIS) causes testicular toxicity. We evaluated the role of …
mechanisms by which cisplatin (CIS) causes testicular toxicity. We evaluated the role of …
Ellagic acid attenuates high-carbohydrate, high-fat diet-induced metabolic syndrome in rats
Background Fruits and nuts may prevent or reverse common human health conditions such
as obesity, diabetes and hypertension; together, these conditions are referred to as …
as obesity, diabetes and hypertension; together, these conditions are referred to as …
Effects of naringin on oxidative stress, inflammation, some reproductive parameters, and apoptosis in acrylamide‐induced testis toxicity in rat
Acrylamide (ACR) is used in many fields such as cosmetics, paper, and textile industries. It
also occurs at very high temperatures in some foods. Gonadotoxic effects of ACR have been …
also occurs at very high temperatures in some foods. Gonadotoxic effects of ACR have been …
Protective effect of rutin on mercuric chloride‐induced reproductive damage in male rats
This study investigated the effects of rutin against reproductive damage caused by toxic
mercury in male rats. Thirty‐five Sprague Dawley rats were used. Control group was injected …
mercury in male rats. Thirty‐five Sprague Dawley rats were used. Control group was injected …
Antioxidative effect of royal jelly in cisplatin-induced testes damage
S Silici, O Ekmekcioglu, G Eraslan, A Demirtas - Urology, 2009 - Elsevier
OBJECTIVES: To investigate the antioxidative effect of royal jelly on cisplatin (CP)-induced
spermiotoxicity using quantitative, biochemical, and histopathologic approaches …
spermiotoxicity using quantitative, biochemical, and histopathologic approaches …