Cancer cachexia: Diagnosis, assessment, and treatment

M Sadeghi, M Keshavarz-Fathi, V Baracos… - Critical reviews in …, 2018 - Elsevier
Cancer cachexia is a multi-factorial syndrome, which negatively affects quality of life,
responsiveness to chemotherapy, and survival in advanced cancer patients. Our …

Diagnosis and outcomes of cachexia in Asia: working consensus report from the Asian Working Group for Cachexia

H Arai, K Maeda, H Wakabayashi… - Journal of cachexia …, 2023 - Wiley Online Library
Chronic diseases often lead to metabolic disorders, causing anabolic resistance and
increased energy consumption, which result in cachexia. Cachexia, in turn, can lead to …

A systematic review examining the relationship between cytokines and cachexia in incurable cancer

DR Paval, R Patton, J McDonald… - Journal of cachexia …, 2022 - Wiley Online Library
Cancer cachexia is an unmet clinical need that affects more than 50% of patients with
cancer. The systemic inflammatory response, which is mediated by a network of cytokines …

Pancreatic cancer associated with obesity and diabetes: an alternative approach for its targeting

R Pothuraju, S Rachagani, WM Junker… - Journal of Experimental …, 2018 - Springer
Background Pancreatic cancer (PC) is among foremost causes of cancer related deaths
worldwide due to generic symptoms, lack of effective screening strategies and resistance to …

Cancer cachexia and skeletal muscle atrophy in clinical studies: what do we really know?

A Dolly, JF Dumas, S Servais - Journal of Cachexia …, 2020 - Wiley Online Library
Research investigators have shown a growing interest in investigating alterations underlying
skeletal muscle wasting in patients with cancer. However, skeletal muscle dysfunctions …

Cachexia in cancer: what is in the definition?

G Vanhoutte, M van de Wiel… - BMJ open …, 2016 - bmjopengastro.bmj.com
Objective This study aimed to provide evidence-based results on differences in overall
survival (OS) rate to guide the diagnosis of cancer cachexia. Design Data collection and …

Pancreatic cancer cachexia: three dimensions of a complex syndrome

M Kordes, L Larsson, L Engstrand, JM Löhr - British journal of cancer, 2021 - nature.com
Cancer cachexia is a multifactorial syndrome that is characterised by a loss of skeletal
muscle mass, is commonly associated with adipose tissue wasting and malaise, and …

Elevated serum interleukin-8 level correlates with cancer-related cachexia and sarcopenia: an indicator for pancreatic cancer outcomes

YC Hou, CJ Wang, YJ Chao, HY Chen… - Journal of clinical …, 2018 - mdpi.com
Cancer cachexia (CC), characterized by body weight loss and sarcopenia, contributes to
over 20% of all cancer-related death. Approximately 80% of pancreatic cancer (PC) patients …

Physical activity as the best supportive care in cancer: the clinician's and the researcher's perspectives

C Torregrosa, F Chorin, EEM Beltran, C Neuzillet… - Cancers, 2022 - mdpi.com
Simple Summary This literature review on adapted physical exercise has been written in
order to raise awareness of medical staff to this central theme in the management of cancer …

Circulating monocyte chemoattractant protein‐1 (MCP‐1) is associated with cachexia in treatment‐naïve pancreatic cancer patients

EE Talbert, HL Lewis, MR Farren… - Journal of cachexia …, 2018 - Wiley Online Library
Background Cancer‐associated wasting, termed cancer cachexia, has a profound effect on
the morbidity and mortality of cancer patients but remains difficult to recognize and …