Spinal cord injury (SCI) leads to loss of motor and sensory function below the injury level
and imposes a considerable burden on patients, families, and society. Repair of the injured …

ABSTRACT A long-standing goal of spinal cord injury research is to develop effective spinal
cord repair strategies for the clinic. Rat models of spinal cord injury provide an important …

Spinal cord injury (SCI) is a devastating neurological disorder that affects thousands of
individuals each year. Over the past decades an enormous progress has been made in our …

Background: Animal spinal cord injury (SCI) models have proved invaluable in better
understanding the mechanisms involved in traumatic SCI and evaluating the effectiveness of …

Numerous strategies have been managed to improve functional recovery after spinal cord
injury (SCI) but an optimal strategy doesn't exist yet. Actually, it is the complexity of the …

Preclinical and clinical studies with various stem cells, their secretomes, and extracellular
vesicles (EVs) indicate their use as a promising strategy for the treatment of various …

Following lesions to the central nervous system, scar tissue forms at the lesion site. Injury
often severs axons and scar tissue is thought to block axonal regeneration, resulting in …

Nuclear magnetic resonance (MR) imaging provides a noninvasive method for studying the
fate of transplanted cells in vivo. We studied, in animals with a cortical photochemical lesion …

In this study, we evaluated if the implantation of allogenic adipose-derived stem cells (ASCs)
improved neurological function in a canine spinal cord injury model. Eleven adult dogs were …

Emerging clinical studies of treating brain and spinal cord injury (SCI) with autologous adult
stem cells led us to compare the effect of an intravenous injection of mesenchymal stem …