Ischaemic heart disease (IHD) remains the leading cause of death and disability in Europe
and worldwide. A major cause of morbidity and mortality in IHD patients is an acute ST …

Lethal reperfusion injury is a paradoxical type of myocardial injury caused by the restoration
of coronary blood flow after an ischemic episode. This review focuses on the mechanisms of …

Most clinically available thermometers accurately report the temperature of whatever tissue
is being measured. The difficulty is that no reliably core-temperature-measuring sites are …

Background: Hypothermia is being used with increasing frequency to prevent or mitigate
various types of neurologic injury. In addition, symptomatic fever control is becoming an …

Increasing evidence suggests that induction of mild hypothermia (32–35° C) in the first hours
after an ischaemic event can prevent or mitigate permanent injuries. This effect has been …

Out-of-hospital cardiac arrest (OHCA) is a common initial presentation of cardiovascular
disease, affecting up to 325 000 people in the United States each year. 1 In a recent meta …

Objectives: The aim of this study was to confirm the cardioprotective effects of hypothermia
using a combination of cold saline and endovascular cooling. Background: Hypothermia has …

Induced hypothermia can be used to protect the brain from post-ischemic and traumatic
neurological injury. Potential clinical applications and the available evidence are discussed …

Background—Experimental studies have shown that induction of hypothermia before
reperfusion of acute coronary occlusion reduces infarct size. Previous clinical studies …

Ischemia reperfusion (IR) injury occurs when blood supply, perfusion, and concomitant
reoxygenation is restored to an organ or area following an initial poor blood supply after a …