Stem cells differentiation into insulin-producing cells (IPCs): recent advances and current challenges
IBB Silva, CH Kimura, VP Colantoni… - Stem cell research & …, 2022 - Springer
Type 1 diabetes mellitus (T1D) is a chronic disease characterized by an autoimmune
destruction of insulin-producing β-pancreatic cells. Although many advances have been …
destruction of insulin-producing β-pancreatic cells. Although many advances have been …
Cryopreservation of human stem cells for clinical application: a review
CJ Hunt - Transfusion Medicine and Hemotherapy, 2011 - karger.com
Stem cells have been used in a clinical setting for many years. Haematopoietic stem cells
have been used for the treatment of both haematological and non-haematological disease; …
have been used for the treatment of both haematological and non-haematological disease; …
Human pluripotent stem cells recurrently acquire and expand dominant negative P53 mutations
Human pluripotent stem cells (hPS cells) can self-renew indefinitely, making them an
attractive source for regenerative therapies. This expansion potential has been linked with …
attractive source for regenerative therapies. This expansion potential has been linked with …
A fully defined and scalable 3D culture system for human pluripotent stem cell expansion and differentiation
Y Lei, DV Schaffer - … of the National Academy of Sciences, 2013 - National Acad Sciences
Human pluripotent stem cells (hPSCs), including human embryonic stem cells and induced
pluripotent stem cells, are promising for numerous biomedical applications, such as cell …
pluripotent stem cells, are promising for numerous biomedical applications, such as cell …
Long-term self-renewal of human pluripotent stem cells on human recombinant laminin-511
S Rodin, A Domogatskaya, S Ström, EM Hansson… - Nature …, 2010 - nature.com
We describe a system for culturing human embryonic stem (hES) cells and induced
pluripotent stem (iPS) cells on a recombinant form of human laminin-511, a component of …
pluripotent stem (iPS) cells on a recombinant form of human laminin-511, a component of …
Clonal culturing of human embryonic stem cells on laminin-521/E-cadherin matrix in defined and xeno-free environment
S Rodin, L Antonsson, C Niaudet, OE Simonson… - Nature …, 2014 - nature.com
Lack of robust methods for establishment and expansion of pluripotent human embryonic
stem (hES) cells still hampers development of cell therapy. Laminins (LN) are a family of …
stem (hES) cells still hampers development of cell therapy. Laminins (LN) are a family of …
Process engineering of human pluripotent stem cells for clinical application
Human pluripotent stem cells (hPSCs), including embryonic and induced pluripotent stem
cells, constitute an extremely attractive tool for cell therapy. However, flexible platforms for …
cells, constitute an extremely attractive tool for cell therapy. However, flexible platforms for …
The spreading, migration and proliferation of mouse mesenchymal stem cells cultured inside hyaluronic acid hydrogels
Synthetic hydrogel scaffolds that can be used as culture systems that mimic the natural stem
cell niche are of increased importance for stem cell biology and regenerative medicine …
cell niche are of increased importance for stem cell biology and regenerative medicine …
Stem cell-biomaterial interactions for regenerative medicine
The synergism of stem cell biology and biomaterial technology promises to have a profound
impact on stem-cell-based clinical applications for tissue regeneration. Biomaterials …
impact on stem-cell-based clinical applications for tissue regeneration. Biomaterials …
Stem cell cultivation in bioreactors
Cell-based therapies have generated great interest in the scientific and medical
communities, and stem cells in particular are very appealing for regenerative medicine, drug …
communities, and stem cells in particular are very appealing for regenerative medicine, drug …