Ellagic acid: Pharmacological activities and molecular mechanisms involved in liver protection

WR García-Niño, C Zazueta - Pharmacological Research, 2015 - Elsevier
Traditional drugs or therapies rarely have effects on regression of chronic liver diseases,
which result in many cases from sustained oxidative stress. In recent years, ellagic acid (EA) …

[HTML][HTML] Antioxidant effects and mechanism of silymarin in oxidative stress induced cardiovascular diseases

A Taleb, KA Ahmad, AU Ihsan, J Qu, NA Lin… - Biomedicine & …, 2018 - Elsevier
Cardiovascular diseases (CVDs) are considered as the major reason for mortality and
morbidity worldwide. Substantial evidence suggests that increased oxidative stress plays a …

Mechanistic insights of hepatoprotective effects of curcumin: Therapeutic updates and future prospects

H Khan, H Ullah, SM Nabavi - Food and Chemical Toxicology, 2019 - Elsevier
The liver is the most essential organ of the body performing vital functions. Hepatic disorders
affect the physiological and biochemical functions of the body. These disorders include …

Hepatoprotective and therapeutic effects of resveratrol: A focus on anti‐inflammatory and antioxidative activities

S Chupradit, D Bokov, MY Zamanian… - Fundamental & …, 2022 - Wiley Online Library
Being the most essential organ in the body, the liver performs critical functions. Hepatic
disorders, such as alcoholic liver disease, hepatic steatosis, liver fibrosis, nonalcoholic fatty …

Anticancer Activity of Rosmarinus officinalis L.: Mechanisms of Action and Therapeutic Potentials

A Allegra, A Tonacci, G Pioggia, C Musolino… - Nutrients, 2020 - mdpi.com
Alternative treatments for neoplastic diseases with new drugs are necessary because the
clinical effectiveness of chemotherapy is often reduced by collateral effects. Several natural …

Coffee reduces liver damage in a rat model of steatohepatitis: the underlying mechanisms and the role of polyphenols and melanoidins

P Vitaglione, F Morisco, G Mazzone, DC Amoruso… - …, 2010 - Wiley Online Library
Epidemiological data associate coffee consumption with a lower prevalence of chronic liver
disease and a reduced risk of elevated liver enzyme levels (γ glutamyl transpeptidase and …

Silymarin modulates the oxidant–antioxidant imbalance during diethylnitrosamine induced oxidative stress in rats

K Pradeep, CVR Mohan, K Gobianand… - European journal of …, 2007 - Elsevier
Oxidative stress is a common mechanism contributing to initiation and progression of
hepatic damage in a variety of liver disorders. Hence, there is a great demand for the …

Phenolic compounds protect HepG2 cells from oxidative damage: relevance of glutathione levels

CF Lima, M Fernandes-Ferreira, C Pereira-Wilson - Life sciences, 2006 - Elsevier
In the present work, the potential hepatoprotective effects of five phenolic compounds
against oxidative damages induced by tert-butyl hydroperoxide (t-BHP) were evaluated in …

[HTML][HTML] Cytoprotective effect of chlorogenic acid against hydrogen peroxide-induced oxidative stress in MC3T3-E1 cells through PI3K/Akt-mediated Nrf2/HO-1 …

D Han, W Chen, X Gu, R Shan, J Zou, G Liu… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Osteoporosis is a disorder of bone and its development is closely associated with oxidative
stress and reactive oxygen species (ROS). Chlorogenic acid (CGA) has potential antioxidant …

Punicalagin induces Nrf2/HO‐1 expression via upregulation of PI3K/AKT pathway and inhibits LPS‐induced oxidative stress in RAW264. 7 macrophages

X Xu, H Li, X Hou, D Li, S He, C Wan… - Mediators of …, 2015 - Wiley Online Library
Reactive oxygen species (ROS) and oxidative stress are thought to play a central role in
potentiating macrophage activation, causing excessive inflammation, tissue damage, and …