The AGC family of serine/threonine kinases (PKA, PKG, PKC) includes more than 60
members that are critical regulators of numerous cellular functions, including cell cycle and …

Disrupted cell polarity is a feature of epithelial cancers. The Crumbs, Par and Scribble
polarity complexes function to specify and maintain apical and basolateral membrane …

Aims Prostate cancer is one of the most frequent causes of cancer death in men worldwide,
and novel drugs for prostate cancer therapies are still being developed. Palmitic acid is a …

NADPH oxidases (NOX) are reactive oxygen species‐(ROS‐) generating enzymes
regulating numerous redox‐dependent signaling pathways. NOX are important regulators of …

Background PCA3 is a non-coding RNA (ncRNA) that is highly expressed in prostate cancer
(PCa) cells, but its functional role is unknown. To investigate its putative function in PCa …

Loss of the tumor suppressor phosphatase and tensin homologue deleted on chromosome
10 (PTEN), which negatively regulates the PI3K–AKT–mTOR pathway, is strongly linked to …

Prostate cancer is a highly prevalent form of cancer that is usually slow-developing and
benign. Due to its high prevalence, it is, however, still the second most common cause of …

Protein kinase C (PKC) is a family of phospholipid‐dependent serine/threonine kinases,
which can be further classified into three PKC isozymes subfamilies: conventional or classic …

Prostate cancer (PCa) is the most commonly diagnosed cancer and second leading cause
of male cancer death in Western nations. Thus, new treatment modalities are urgently …

The purpose of this study was to test the hypothesis that cooperative interaction between
cutaneous fatty acid-binding protein (C-FABP) and peroxisome proliferator-activated …