Amyloid diseases are global epidemics with profound health, social and economic
implications and yet remain without a cure. This dire situation calls for research into the …

Self-assembled peptide and protein amyloid nanostructures have traditionally been
considered only as pathological aggregates implicated in human neurodegenerative …

Proteinaceous materials based on the amyloid core structure have recently been discovered
at the origin of biological functionality in a remarkably diverse set of roles, and attention is …

The cross-β amyloid form of peptides and proteins represents an archetypal and widely
accessible structure consisting of ordered arrays of β-sheet filaments. These complex …

Amyloid or amyloid-like fibrils represent a general class of nanomaterials that can be formed
from many different peptides and proteins. Although these structures have an important role …

The development of vaccines and other immunotherapies has been complicated by
heterogeneous antigen display and the use of incompletely defined immune adjuvants with …

We report here the design of a biomimetic nanofibrous hydrogel as a 3D-scaffold for
anchorage-dependent cells. The peptide-based bioactive hydrogel is formed through …

Amyloid functional materials from amyloid fibril building blocks, produced in vitro from
amyloidogenic natural proteins or synthetic peptides, show diverse functionalities ranging …

The use of self-assembly for the construction of functional biomaterials is a highly promising
and exciting area of research, with great potential for the treatment of injury or disease. By …

Many diseases including cardiovascular disease, diabetes, osteoporosis, and cancers
cannot be treated effectively with current clinical therapy because of a significant reduction …