Considerable efforts have been devoted to the development of novel functionalized
nanomaterials for bio-oriented applications. With unique optical properties and molar scale …

This Review addresses methods for obtaining sequence information directly from
unamplified genomic length DNA. Our generic starting point is a large piece of DNA that …

Atomic force microscopy is an amazing technique that allies a versatile methodology (that
allows measurement of samples in liquid, vacuum or air) to imaging with unprecedented …

The study of electronic properties of materials at the nanoscale has unveiled physical laws
and generated materials such as nanoparticles, quantum dots, nanodiamonds …

Next generation sequencing (NGS) is revolutionizing all fields of biological research but it
fails to extract the full range of information associated with genetic material. Optical mapping …

Quantum dots (QDs) are inorganic semiconductor nanocrystals that have unique
optoelectronic properties responsible for bringing together multidisciplinary research to …

In the past two decades, nanoscale advanced materials have been explored for biosensing
molecules, so new horizons have opened up for identifying and quantifying biomolecules …

For imaging with different modalities, labels, which provide contrast for all modalities, are
required. Colloidal nanoparticles composed out of an inorganic core and a polymer shell …

We demonstrate the use of a microfluidic stagnation point flow to trap and extend single
molecules of double-stranded (ds) genomic DNA for detection of target sequences along the …

Herein we report the specific labelling of the epigenetic modification 5-hydroxymethyl-
cytosine along genomic DNA molecules with a fluorescent reporter molecule. Enzymatic …