Non-alkaloid cholinesterase inhibitory compounds from natural sources

AN Tamfu, S Kucukaydin, B Yeskaliyeva, M Ozturk… - Molecules, 2021 - mdpi.com
Alzheimer's disease (AD) is a severe neurodegenerative disorder of different brain regions
accompanied by distresses and affecting more than 25 million people in the world. This …

Does the application of acetylcholinesterase inhibitors in the treatment of Alzheimer's disease lead to depression?

M Mitić, T Lazarević-Pašti - Expert Opinion on Drug Metabolism & …, 2021 - Taylor & Francis
Introduction: Alzheimer's disease and depression are health conditions affecting millions of
people around the world. Both are strongly related to the level of the neurotransmitter …

Acetylcholinesterase inhibitory activity of Ferula plants and their potential for treatment of Alzheimer's disease

SM Bagheri, M Allahtavakoli, A Moradi - Journal of Complementary …, 2023 - degruyter.com
One of the current strategies in the treatment of Alzheimer's disease is using drugs with
acetylcholinesterase (AChE) inhibitory property. The existence of various compounds in …

Isolation and purification of terpenoid compounds from Ferula haussknechtii and evaluation of their antibacterial effects

Z Arjmand, M Hamburger, D Dastan - Natural Product Research, 2023 - Taylor & Francis
The roots of F. haussknechtii are used by local people in order to treat wounds and urinary
infections. Ferula species are rich in bioactive compounds with biological effects. In line with …

Sesquiterpenes and Sesquiterpene Derivatives from Ferula: Their Chemical Structures, Biosynthetic Pathways, and Biological Properties

J Wang, Q Zheng, H Wang, L Shi, G Wang, Y Zhao… - Antioxidants, 2023 - mdpi.com
Ferula is a genus of flowering plants known for its edible and medicinal properties. Since
ancient times, many species of Ferula have been used in traditional medicine to treat …

[PDF][PDF] Vilazodone-Tacrine hybrids as potential anti-Alzheimer agents: QSAR, molecular docking, and molecular dynamic (MD) simulation studies

H Abbasi, M Fereidoonnezhad… - Biointerface Res. Appl …, 2021 - researchgate.net
Alzheimer's disease (AD) is a type of functional impairment of the brain, which gently
degrades the patients' mental potency. The goal pursued in this study is to introduce novel …

Chimgin from Ferula haussknechtii as AChE inhibitor and confirmation of the absolute configuration

N Feyzi, A Ebadi, D Dastan - Journal of Biomolecular Structure and …, 2023 - Taylor & Francis
Alzheimer's disease (AD) is the most common cause of dementia worldwide and is classified
as a neurodegenerative disorder. From a drug design perspective, natural products (NPs) …

Cholinesterase Inhibitory Compounds from Peltophorum Pterocarpum Flowers

JA Monehin, AO Oriola, IJ Olawuni, SA Odediran… - Chemistry Africa, 2024 - Springer
Neurodegenerative disorders (NDs), such as Alzheimer's and Parkinson disease, affect
millions of people worldwide. Natural cholinesterase inhibitors are an important class of lead …

[PDF][PDF] 基于靶点机制的抗阿尔茨海默病天然活性成分研究进展

黄丹蓉, 程亚敏, 冯紫涵, 申刚义 - 天然产物研究与开发, 2023 - trcw.ac.cn
中央民族大学药学院民族医药教育部重点实验室(中央民族大学), 北京100081 摘要:
阿尔茨海默病(Alzheimer's disease, AD) 作为神经系统退行性疾病, 发病率随着年龄增长而显著 …

Chemical Composition and Antibacterial Activity of the Leutea elbursensis Mozaff. Essential Oil from Dried Aerial Parts and Rhizome

S Khalil-Moghaddam, R Moghimi… - Journal of Essential Oil …, 2022 - Taylor & Francis
Natural products are among the safe sources to produce and survey new bioactive
compounds. Leutea elbursensis Mozaff.(Apiaceae) is an endemic and wild plant in Iran …