Rational design of cancer nanomedicine: nanoproperty integration and synchronization

Q Sun, Z Zhou, N Qiu, Y Shen - Advanced materials, 2017 - Wiley Online Library
Current cancer nanomedicines can only mitigate adverse effects but fail to enhance
therapeutic efficacies of anticancer drugs. Rational design of next‐generation cancer …

Supramolecular chemotherapy based on host–guest molecular recognition: a novel strategy in the battle against cancer with a bright future

J Zhou, G Yu, F Huang - Chemical Society Reviews, 2017 - pubs.rsc.org
Chemotherapy is currently one of the most effective ways to treat cancer. However,
traditional chemotherapy faces several obstacles to clinical trials, such as poor …

Photoresponsive luminescent polymeric hydrogels for reversible information encryption and decryption

Z Li, H Chen, B Li, Y Xie, X Gong, X Liu, H Li… - Advanced …, 2019 - Wiley Online Library
Conventional luminescent information is usually visible under either ambient or UV light,
hampering their potential application in smart confidential information protection. In order to …

[HTML][HTML] Biomedical applications of supramolecular systems based on host–guest interactions

X Ma, Y Zhao - Chemical reviews, 2015 - ACS Publications
The development of supramolecular chemistry dates back to 1987 when Lehn, Cram, and
Pedersen won the Nobel Prize on account of their leading discoveries in the host–guest …

Supramolecular amphiphiles based on host–guest molecular recognition motifs

G Yu, K Jie, F Huang - Chemical reviews, 2015 - ACS Publications
Self-assembly, which makes use of molecules rather than atomic units, offers a bottom-up
approach to the construction of new materials on multiple length scales.(1-9) By precisely …

Gated materials for on-command release of guest molecules

E Aznar, M Oroval, L Pascual, JR Murguía… - Chemical …, 2016 - ACS Publications
Multidisciplinary research at the forefront of the field of hybrid materials has paved the way to
the development of endless examples of smart devices. One appealing concept in this fertile …

“Combo” nanomedicine: co-delivery of multi-modal therapeutics for efficient, targeted, and safe cancer therapy

JA Kemp, MS Shim, CY Heo, YJ Kwon - Advanced drug delivery reviews, 2016 - Elsevier
The dynamic and versatile nature of diseases such as cancer has been a pivotal challenge
for developing efficient and safe therapies. Cancer treatments using a single therapeutic …

Multifunctional mesoporous silica nanoparticles as a universal platform for drug delivery

C Argyo, V Weiss, C Bräuchle, T Bein - Chemistry of materials, 2014 - ACS Publications
Nanosized mesoporous silica particles with high colloidal stability attract growing attention
as drug delivery systems for targeted cancer treatment and as bioimaging devices. This …

[HTML][HTML] Engineering blood exosomes for tumor-targeting efficient gene/chemo combination therapy

Q Zhan, K Yi, H Qi, S Li, X Li, Q Wang, Y Wang… - Theranostics, 2020 - ncbi.nlm.nih.gov
Rationale: Developing an effective nanoplatform to realize'multi-in-one'is essential to
broaden the therapeutic potential of combination therapy. Exosomes are ideal candidates …

A drug‐self‐gated mesoporous antitumor nanoplatform based on pH‐sensitive dynamic covalent bond

X Zeng, G Liu, W Tao, Y Ma, X Zhang… - Advanced Functional …, 2017 - Wiley Online Library
To achieve on‐demand drug release, mesoporous silica nanocarriers as antitumor platforms
generally need to be gated with stimuli‐responsive capping agents. Herein, a “smart” …