Proteins of the actin depolymerizing factor (ADF)/cofilin family are ubiquitous among
eukaryotes and are essential regulators of actin dynamics and function. Mammalian neurons …

Actin is a versatile and ubiquitous cytoskeletal protein that plays a major role in both the
establishment and the maintenance of neuronal polarity. For a long time, the most prominent …

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by Aβ-driven
synaptic dysfunction in the early phases of pathogenesis. In the synaptic context, the actin …

All eukaryotic cells are composed of the cytoskeleton, which plays crucial roles in
coordinating diverse cellular functions such as cell division, morphology, migration …

The lateral septum (LS), a GABAergic structure located in the basal forebrain, is implicated
in social behavior, learning, and memory. We previously demonstrated that expression of …

Cyclase-associated protein (CAP) has been discovered three decades ago in budding yeast
as a protein that associates with the cyclic adenosine monophosphate (cAMP)-producing …

Cyclase-associated protein (CAP) is an actin binding protein that has been initially
described as partner of the adenylyl cyclase in yeast. In all vertebrates and some …

Neurological diseases are among the leading causes of disability and death worldwide and
remain difficult to treat. Tissue engineering offers avenues to test potential treatments; …

Regulation of actin cytoskeleton dynamics in dendritic spines is crucial for learning and
memory formation. Hence, defects in the actin cytoskeleton pathways are a biological trait of …

Actin filaments (F-actin) are key components of sarcomeres, the basic contractile units of
skeletal muscle myofibrils. A crucial step during myofibril differentiation is the sequential …