Virtual screening and molecular dynamics simulations provide insight into repurposing drugs against SARS-CoV-2 variants Spike protein/ACE2 interface
After over two years of living with Covid-19 and hundreds of million cases worldwide there is
still an unmet need to find proper treatments for the novel coronavirus, due also to the rapid …
still an unmet need to find proper treatments for the novel coronavirus, due also to the rapid …
In silico discovery of small molecule modulators targeting the Achilles' heel of SARS-CoV-2 spike protein
Q Wang, F Meng, Y Xie, W Wang, Y Meng… - ACS Central …, 2023 - ACS Publications
The spike protein of SARS-CoV-2 has been a promising target for developing vaccines and
therapeutics due to its crucial role in the viral entry process. Previously reported cryogenic …
therapeutics due to its crucial role in the viral entry process. Previously reported cryogenic …
Induced pluripotent stem cells (iPSCs): molecular mechanisms of induction and applications
The induced pluripotent stem cell (iPSC) technology has transformed in vitro research and
holds great promise to advance regenerative medicine. iPSCs have the capacity for an …
holds great promise to advance regenerative medicine. iPSCs have the capacity for an …
The Apolipoprotein E neutralizing antibody inhibits SARS‐CoV‐2 infection by blocking cellular entry of lipoviral particles
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is the causal agent for
coronavirus disease 2019 (COVID‐19). Although vaccines have helped to prevent …
coronavirus disease 2019 (COVID‐19). Although vaccines have helped to prevent …
Directed Differentiation of Neurons from Human iPSCs for Modeling Neurological Disorders
C Wang, J Cerneckis, Y Shi - Cerebral Cortex Development: Methods and …, 2024 - Springer
Human-induced pluripotent stem cell (hiPSC) technology has enabled comprehensive
human cell-based disease modeling in vitro. Due to limited accessibility of primary human …
human cell-based disease modeling in vitro. Due to limited accessibility of primary human …