The total and regional peripheral resistance and capacitance of the vascular system is
regulated by the sympathetic nervous system, which influences the vasculature mainly …

Abstract Using [3 H] para-aminoclonidine, α 2 adrenergic binding sites have been mapped
in the rat and human CNS using in vitro labeling autoradiographic techniques. In both the rat …

Different studies have led to our present knowledge of the membrane receptors responsible
for mediating the responses to the endogenous catecholamines. These receptors were …

The a, ARs are important mediators of sympathetic nervous system responses, particularly
those involved in cardiovascular homeostasis, such as arteriolar smooth muscle constriction …

To investigate the physiological role of the α1D-adrenergic receptor (α1D-AR) subtype, we
created mice lacking the α1D-AR (α1D–/–) by gene targeting and characterized their …

Adipocytes can be readily isolated from intact adipose tissue. In adipocytes from hamster
and human white adipose tissue it is possible to demonstrate beta, alpha 1, and alpha 2 …

Several reviews of coronary physiology have been published in the last decade (Bassenge
1984; Berne and Rubio 1979; Feigl 1983). The purpose of the present review is to provide …

alpha-Adrenoceptor-mediated effects of sympathetic activation on the heart and coronary
circulation are reviewed with emphasis on the pathophysiology of myocardial ischemia. A …

The control and maintenance of vascular tone is due to a balance between vasoconstrictor
and vasodilator pathways. Vasomotor responses to neural, metabolic and physical factors …

1 We examined whether α1‐adrenoceptors in various blood vessels can be divided into
subtypes by antagonist affinity or by susceptibility to chloroethylclonidine or nifedipine. 2 …