New insights into rosacea pathophysiology: a review of recent findings
M Steinhoff, J Schauber, JJ Leyden - Journal of the American Academy of …, 2013 - Elsevier
Rosacea is a common, chronic inflammatory skin disease of poorly understood origin.
Based on its clinical features (flushing, chronic inflammation, fibrosis) and trigger factors, a …
Based on its clinical features (flushing, chronic inflammation, fibrosis) and trigger factors, a …
The molecular pathology of rosacea
K Yamasaki, RL Gallo - Journal of dermatological science, 2009 - Elsevier
Rosacea is a common and chronic inflammatory skin disease that affects over 10 million
Americans. Although the phenotypes of rosacea are clinically heterogeneous, they are all …
Americans. Although the phenotypes of rosacea are clinically heterogeneous, they are all …
Redox regulation of cell migration and adhesion
Reactive oxygen species (ROS), particularly hydrogen peroxide, and the proteins that
regulate them play important roles in the migration and adhesion of cells. Stimulation of cell …
regulate them play important roles in the migration and adhesion of cells. Stimulation of cell …
Interaction of pattern recognition receptors with Mycobacterium tuberculosis
Tuberculosis (TB) is considered a major worldwide health problem with 10 million new
cases diagnosed each year. Our understanding of TB immunology has become greater and …
cases diagnosed each year. Our understanding of TB immunology has become greater and …
The many roles of NOX2 NADPH oxidase-derived ROS in immunity
GY Lam, J Huang, JH Brumell - Seminars in immunopathology, 2010 - Springer
Reactive oxygen species (ROS) have long been studied in the context of their direct toxic
effects on cells. As a result, ROS have conventionally been thought of as a necessary …
effects on cells. As a result, ROS have conventionally been thought of as a necessary …
[HTML][HTML] Rosacea: the cytokine and chemokine network
Rosacea is one of the most common dermatoses of adults. Recent studies have improved
our understanding of the pathophysiology of rosacea. Current concepts suggest that known …
our understanding of the pathophysiology of rosacea. Current concepts suggest that known …
Reactive oxygen species drive herpes simplex virus (HSV)-1-induced proinflammatory cytokine production by murine microglia
S Hu, WS Sheng, SJ Schachtele… - Journal of …, 2011 - Springer
Background Production of reactive oxygen species (ROS) and proinflammatory cytokines by
microglial cells in response to viral brain infection contributes to both pathogen clearance …
microglial cells in response to viral brain infection contributes to both pathogen clearance …
[HTML][HTML] Host-mycobacteria conflict: Immune responses of the host vs. the mycobacteria TLR2 and TLR4 ligands and concomitant host-directed therapy
KP Pattanaik, S Sengupta, BP Jit, R Kotak… - Microbiological …, 2022 - Elsevier
Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), is one of the most grievous
infectious diseases with long-term morbidity and unpredicted mortality rates globally. Thus …
infectious diseases with long-term morbidity and unpredicted mortality rates globally. Thus …
Microglial activation of the NLRP3 inflammasome by the priming signals derived from macrophages infected with mycobacteria
HM Lee, J Kang, SJ Lee, EK Jo - Glia, 2013 - Wiley Online Library
The inflammasome is a multimolecular complex that orchestrates the activation of
proinflammatory caspases and interleukin (IL)‐1β, which is generally increased in the …
proinflammatory caspases and interleukin (IL)‐1β, which is generally increased in the …
Early secreted antigenic target of 6 kDa (ESAT-6) protein of Mycobacterium tuberculosis induces interleukin-8 (IL-8) expression in lung epithelial cells via protein …
V Boggaram, KR Gottipati, X Wang, B Samten - Journal of Biological …, 2013 - ASBMB
Early secreted antigenic target of 6 kDa (ESAT-6) of Mycobacterium tuberculosis is critical
for the virulence and pathogenicity of M. tuberculosis. IL-8, a major chemotactic cytokine for …
for the virulence and pathogenicity of M. tuberculosis. IL-8, a major chemotactic cytokine for …