Patent ductus arteriosus in preterm infants: do we have the right answers?

H Abdel-Hady, N Nasef, AE Shabaan… - BioMed Research …, 2013 - Wiley Online Library
Patent ductus arteriosus (PDA) is a common clinical condition in preterm infants. Preterm
newborns with PDA are at greater risk for several morbidities, including higher rates of …

Recent advances in the treatment of preterm newborn infants with patent ductus arteriosus

H Sallmon, P Koehne… - Clinics in …, 2016 - perinatology.theclinics.com
The ductus arteriosus (DA) is a fetal shunt vessel that, during prenatal life, diverts blood
away from the pulmonary circulation into the systemic circulation toward the placenta …

Oral paracetamol versus oral ibuprofen in the management of patent ductus arteriosus in preterm infants: a randomized controlled trial

MY Oncel, S Yurttutan, O Erdeve, N Uras, N Altug… - The Journal of …, 2014 - Elsevier
Objective To compare the efficacy and safety of oral paracetamol and oral ibuprofen for the
pharmacological closure of patent ductus arteriosus (PDA) in preterm infants. Study design …

Efficacy and safety of oral paracetamol versus oral ibuprofen for closure of patent ductus arteriosus in preterm infants: a randomized controlled trial

RA El-Farrash, MS El Shimy, AS El-Sakka… - The journal of …, 2019 - Taylor & Francis
Objective: The objective of this study is to evaluate the efficacy and safety of oral
paracetamol versus oral ibuprofen in the treatment of hemodynamically significant patent …

[HTML][HTML] Efficacy of paracetamol on patent ductus arteriosus closure may be dose dependent: evidence from human and murine studies

A El-Khuffash, A Jain, D Corcoran, PS Shah… - Pediatric …, 2014 - nature.com
Background: We evaluated the clinical effectiveness of variable courses of paracetamol on
patent ductus arteriosus (PDA) closure and examined its effect on the in vitro term and …

[HTML][HTML] Efficacy of paracetamol for the treatment of patent ductus arteriosus in preterm neonates

G Terrin, F Conte, A Scipione, E Bacchio… - Italian journal of …, 2014 - Springer
Inhibitors of the cyclo-oxygenase component of prostaglandin-H 2 synthetase, namely
indomethacin and ibuprofen, are commonly used in the treatment of hemodynamically …

Paracetamol therapy for patent ductus arteriosus in premature infants: a chance before surgical ligation

ÖMA Özdemir, M Doğan, K Küçüktaşçı, H Ergin… - Pediatric …, 2014 - Springer
Patent ductus arteriosus (PDA) remains a common problem in premature infants. Treatment
options include pharmacologic therapy and surgical ligation, but these are associated with …

[HTML][HTML] Oral medications regarding their safety and efficacy in the management of patent ductus arteriosus

MY Oncel, O Erdeve - World journal of clinical pediatrics, 2016 - ncbi.nlm.nih.gov
Patent ductus arteriosus (PDA) is a common clinical condition in preterm infants which is
inversely related to birth weight and gestational age. Cyclooxygenase inhibitors such as …

[HTML][HTML] Limited effects of intravenous paracetamol on patent ductus arteriosus in very low birth weight infants with contraindications for ibuprofen or after ibuprofen …

DWE Roofthooft, IM van Beynum, JCA de Klerk… - European journal of …, 2015 - Springer
Finding the optimal pharmacological treatment of a patent ductus arteriosus (PDA) in
preterm neonates remains challenging. There is a growing interest in paracetamol as a new …

Intravenous paracetamol for PDA closure in the preterm: a single-center experience

E Valerio, MR Valente, S Salvadori, AC Frigo… - European journal of …, 2016 - Springer
Increasing recent evidence favors paracetamol use for patent ductus arteriosus (PDA)
closure in preterms. Our study aims were (1) to assess efficacy and safety of intravenous (iv) …