The therapeutic potential of natural dietary flavonoids against SARS-CoV-2 infection

Z Wang, L Yang - Nutrients, 2023 - mdpi.com
The exploration of non-toxic and cost-effective dietary components, such as epigallocatechin
3-gallate and myricetin, for health improvement and disease treatment has recently attracted …

Theoretical Insights into the Oxidative Stress-Relieving Properties of Pinocembrin─ An Isolated Flavonoid from Honey and Propolis

M Spiegel - The Journal of Physical Chemistry B, 2023 - ACS Publications
Bee products are a valuable group of substances that have a wide range of applications for
humans. They contain a high level of polyphenolic compounds, which have been shown to …

Computational assessment of the primary and secondary antioxidant potential of alkylresorcinols in physiological media

H Boulebd, M Spiegel - RSC advances, 2023 - pubs.rsc.org
Alkylresorcinols are a group of natural phenolic compounds found in various foods such as
whole grain cereals, bread, and certain fruits. They are known for their beneficial health …

Understanding prominent effects of the intramolecular hydrogen bond on the photophysical properties and antiradical abilities of six flavonoids

Y Zhang, C Shang, C Sun, L Wang - Journal of Molecular Liquids, 2023 - Elsevier
The photophysical properties and antiradical abilities of 5-Hydroxyflavone, 3, 5-
Dihydroxyflavone, galangin, kaempferol, quercetin, and myricetin are explored using density …

Unveiling the Antioxidative Potential of Galangin: Complete and Detailed Mechanistic Insights through Density Functional Theory Studies

M Spiegel - The Journal of Organic Chemistry, 2024 - ACS Publications
A comprehensive quantum mechanical investigation delved into the antioxidative activity of
galangin (Glg). Thermochemical and kinetic data were used to assess antiradical, chelating …

[HTML][HTML] On the dual role of (+)-catechin as primary antioxidant and inhibitor of viral proteases

G Ciardullo, C Orlando, N Russo, E Marchese… - Computers in Biology …, 2024 - Elsevier
Natural antioxidants have become the subject of many investigations due to the role that
they play in the reduction of oxidative stress. Their main scavenging mechanisms concern …

Primary Antioxidant Power and Mpro SARS‐CoV‐2 Non‐Covalent Inhibition Capabilities of Miquelianin

M Spiegel, M Prejanò, N Russo… - Chemistry–An Asian …, 2024 - Wiley Online Library
The antioxidant power of quercetin‐3‐O‐glucuronide (miquelianin) has been studied, at the
density functional level of theory, in both lipid‐like and aqueous environments. In the …

Unveiling the Anti-Radical Potential of Galangin—A Detailed Density Functional Theory Investigation

M Spiegel - 2024 - chemrxiv.org
A comprehensive quantum mechanical investigation into the antiradical activity of galangin
(Glg), a natural flavonoid recognized for its robust antioxidant and anti-inflammatory …