Membrane and nuclear estrogen receptor alpha actions: from tissue specificity to medical implications

JF Arnal, F Lenfant, R Metivier, G Flouriot… - Physiological …, 2017 - journals.physiology.org
Estrogen receptor alpha (ERα) has been recognized now for several decades as playing a
key role in reproduction and exerting functions in numerous nonreproductive tissues. In this …

Treating patients with “thin” endometrium–an ongoing challenge

O Lebovitz, R Orvieto - Gynecological Endocrinology, 2014 - Taylor & Francis
Objective: To review the literature regarding inadequate growth (“thin”) of the endometrium
and to present the hitherto published methods aimed to improve endometrial thickness and …

[HTML][HTML] Rate of true recurrent implantation failure is low: results of three successive frozen euploid single embryo transfers

P Pirtea, D De Ziegler, X Tao, L Sun, Y Zhan… - Fertility and sterility, 2021 - Elsevier
Objective To study the true prevalence of recurrent implantation failure. Design
Retrospective cohort study. Setting A private assisted reproductive technology center …

LPA3-mediated lysophosphatidic acid signalling in embryo implantation and spacing

X Ye, K Hama, JJA Contos, B Anliker, A Inoue… - Nature, 2005 - nature.com
Every successful pregnancy requires proper embryo implantation. Low implantation rate is a
major problem during infertility treatments using assisted reproductive technologies. Here …

Does the endometrial receptivity array really provide personalized embryo transfer?

R Bassil, R Casper, N Samara, TB Hsieh… - Journal of Assisted …, 2018 - Springer
Purpose The aim of the present study was to determine the percentage of infertility patients
who are diagnosed with a non-receptive endometrium according to the endometrial …

Lessons in estrogen biology from knockout and transgenic animals

SC Hewitt, JC Harrell, KS Korach - Annu. Rev. Physiol., 2005 - annualreviews.org
▪ Abstract Tremendous progress has been made in elucidating numerous critical aspects of
estrogen signaling. New tools and techniques have enabled detailed molecular analysis of …

Implantation of the human embryo requires Rac1-dependent endometrial stromal cell migration

S Grewal, JG Carver, AJ Ridley… - Proceedings of the …, 2008 - National Acad Sciences
Failure of the human embryo to implant into the uterine wall during the early stages of
pregnancy is a major cause of infertility. Implantation involves embryo apposition and …

Exogenous amino acids regulate trophectoderm differentiation in the mouse blastocyst through an mTOR-dependent pathway

PM Martin, AE Sutherland - Developmental biology, 2001 - Elsevier
At the late blastocyst stage, the epithelial trophectoderm cells of the mammalian embryo
undergo a phenotypic change that allows them to invade into the uterine stroma and make …

In-vitro model systems for the study of human embryo–endometrium interactions

CHE Weimar, EDP Uiterweer, G Teklenburg… - Reproductive …, 2013 - Elsevier
Implantation requires highly orchestrated interactions between the developing embryo and
maternal endometrium. The association between abnormal implantation and reproductive …

Aquaporin water channel genes are differentially expressed and regulated by ovarian steroids during the periimplantation period in the mouse

C Richard, JU Gao, N Brown, J Reese - Endocrinology, 2003 - academic.oup.com
The periimplantation period is marked by edematous changes in the uterus. In the mouse,
increased uterine vascular permeability occurs in response to estrogen and certain …