Multiple roles of chitosan in mucosal drug delivery: an updated review

P Mura, F Maestrelli, M Cirri, N Mennini - Marine Drugs, 2022 - mdpi.com
Chitosan (CS) is a linear polysaccharide obtained by the deacetylation of chitin, which, after
cellulose, is the second biopolymer most abundant in nature, being the primary component …

Polymeric nanoparticles for antimicrobial therapies: An up-to-date overview

VA Spirescu, C Chircov, AM Grumezescu… - Polymers, 2021 - mdpi.com
Despite the many advancements in the pharmaceutical and medical fields and the
development of numerous antimicrobial drugs aimed to suppress and destroy pathogenic …

Nanocomposite based on gold nanoparticles and carboxymethyl cellulose: synthesis, characterization, antimicrobial, and anticancer activities

AS Doghish, AH Hashem, AM Shehabeldine… - Journal of Drug Delivery …, 2022 - Elsevier
The current study fabricated a nanocomposite based on gold nanoparticles and carboxy
methyl cellulose (CMC-AuNPs). The prepared nanocomposite (CMC-AuNPs) was fully …

Fungal quorum-sensing molecules and inhibitors with potential antifungal activity: a review

A Mehmood, G Liu, X Wang, G Meng, C Wang, Y Liu - Molecules, 2019 - mdpi.com
The theory of persisting independent and isolated regarding microorganisms is no longer
accepted. To survive and reproduce they have developed several communication platforms …

Therapies and vaccines based on nanoparticles for the treatment of systemic fungal infections

B Kischkel, SA Rossi, SR Santos… - Frontiers in cellular …, 2020 - frontiersin.org
Treatment modalities for systemic mycoses are still limited. Currently, the main antifungal
therapeutics include polyenes, azoles, and echinocandins. However, even in the setting of …

Fungal Quorum-Sensing Molecules: A Review of Their Antifungal Effect against Candida Biofilms

R Kovács, L Majoros - Journal of Fungi, 2020 - mdpi.com
The number of effective therapeutic strategies against biofilms is limited; development of
novel therapies is urgently needed to treat a variety of biofilm-associated infections. Quorum …

The expanded role of chitosan in localized antimicrobial therapy

LM Hemmingsen, N Škalko-Basnet, MW Jøraholmen - Marine Drugs, 2021 - mdpi.com
Chitosan is one of the most studied natural origin polymers for biomedical applications. This
review focuses on the potential of chitosan in localized antimicrobial therapy to address the …

[HTML][HTML] Chitosan-based systems aimed at local application for vaginal infections

VHS Araujo, MPC de Souza, GC Carvalho… - Carbohydrate …, 2021 - Elsevier
Vaginal administration is a promising route for the local treatment of infectious vaginal
diseases since it can bypass the first-pass metabolism, drug interactions, and adverse …

Novel nanocarrier of miconazole based on chitosan-coated iron oxide nanoparticles as a nanotherapy to fight Candida biofilms

LS Arias, JP Pessan, FN de Souza Neto… - Colloids and Surfaces B …, 2020 - Elsevier
Overexposure of microorganisms to conventional drugs has led to resistant species that
require new treatment strategies. This study prepared and characterized a nanocarrier of …

In vitro and in vivo Effect of Exogenous Farnesol Exposure Against Candida auris

F Nagy, E Vitális, Á Jakab, AM Borman… - Frontiers in …, 2020 - frontiersin.org
The spreading of multidrug-resistant Candida auris is considered as an emerging global
health threat. The number of effective therapeutic regimens is strongly limited; therefore …