Developing biomedical engineering technologies for reproductive medicine

Y Zhu, B Kong, R Liu, Y Zhao - Smart Medicine, 2022 - Wiley Online Library
Infertility is a rising global health issue with a far‐reaching impact on the socioeconomic
livelihoods. As there are highly complex causes of male and female infertility, it is highly …

Jeffery's orbits and microswimmers in flows: A theoretical review

K Ishimoto - Journal of the Physical Society of Japan, 2023 - journals.jps.jp
In this review, we provide a theoretical introduction to Jeffery's equations for the orientation
dynamics of an axisymmetric object in a flow at low Reynolds number, and review recent …

High-DNA integrity sperm selection using rheotaxis and boundary following behavior in a microfluidic chip

S Zeaei, MZ Targhi, I Halvaei, R Nosrati - Lab on a Chip, 2023 - pubs.rsc.org
Rheotaxis, as one of the main natural guidance mechanisms in vivo, has been used in
microfluidics to separate motile sperm. However, the lack of DNA integrity assessment and …

[HTML][HTML] Biological benefits of collective swimming of sperm in a viscoelastic fluid

S Phuyal, SS Suarez, CK Tung - Frontiers in Cell and Developmental …, 2022 - frontiersin.org
Collective swimming is evident in the sperm of several mammalian species. In bull (Bos
taurus) sperm, high viscoelasticity of the surrounding fluid induces the sperm to form …

Microfluidics: The future of sperm selection in assisted reproduction

AR Jahangiri, N Ziarati, E Dadkhah, MN Bucak… - …, 2024 - Wiley Online Library
Background Obtaining functional sperm cells is the first step to treat infertility. With the ever‐
increasing trend in male infertility, clinicians require access to effective solutions that are …

[HTML][HTML] RT-LAMP-based molecular diagnostic set-up for rapid hepatitis C virus testing

S Sharma, E Thomas, M Caputi, W Asghar - Biosensors, 2022 - mdpi.com
Hepatitis C virus (HCV) infections occur in approximately 3% of the world population. The
development of an enhanced and extensive-scale screening is required to accomplish the …

Bio-inspired progressive motile sperm separation using joint rheotaxis and boundary-following behavior

MB Tabalvandani, S Javadizadeh, M Badieirostami - Lab on a Chip, 2024 - pubs.rsc.org
Infertility, as a daunting ever-increasing challenge, poses a worldwide issue to both couples
and the healthcare sector. According to the World Health Organization, half of infertility …

Microfluidic chip as a promising evaluation method in assisted reproduction: A systematic review

T Wu, Y Wu, J Yan, J Zhang… - … & Translational Medicine, 2024 - Wiley Online Library
The aim of assisted reproductive technology (ART) is to select the high‐quality sperm,
oocytes, and embryos, and finally achieve a successful pregnancy. However, functional …

High-throughput selection of sperm with improved DNA integrity and rapidly progressive motility using a butterfly-shaped chip compared to the swim-up method

AS Asl, MZ Targhi, S Zeaei, I Halvaei, R Nosrati - Lab on a Chip, 2024 - pubs.rsc.org
Microfluidics provides unique opportunities for the high throughput selection of motile sperm
with improved DNA integrity for assisted reproductive technologies (ARTs). Here, through a …

Faster sperm selected by rheotaxis leads to superior early embryonic development in vitro

M Yaghoobi, A Abdelhady, A Favakeh, P Xie… - Lab on a Chip, 2024 - pubs.rsc.org
To understand the impact of sperm speed as they swim against the flow on fertilization rates,
we created conditions similar to the female reproductive tract (FRT) on a microfluidic …