Labor resembles an inflammatory response that includes secretion of cytokines/chemokines
by resident and infiltrating immune cells into reproductive tissues and the maternal/fetal …

Immune cells in the placental bed are important for adequate development of the placental
bed. The most prominent immune cells in the placental bed early in pregnancy are uterine …

Human chorionic gonadotropin (hCG) serves as one of the first signals provided by the
embryo to the mother. Exactly at the time when the first step of the implantation process is …

Mast cells (MC) are hemotopoietically derived tissue immune cells that are ubiquitous in the
body, including neuroendocrine organs such as the hypothalamus, pineal, pituitary, ovaries …

The immune system matters. Several areas of clinical relevance should come to mind. First,
regulation of the immune system is thought to play a role in both male and female fertility, 1 …

Implantation of the fertilized egg into the maternal uterus is a crucial step in pregnancy
establishment. Increasing evidence suggests that its success depends on various cell types …

Human labour is an inflammatory event, physiologically driven by an interaction between
hormonal and mechanical factors and pathologically associated with infection, bleeding and …

Various physiologically relevant processes are regulated by the interaction of the receptor
tyrosine kinase (c-Kit) and its ligand stem cell factor (SCF), with SCF known to be the most …

In preparation for delivery, the uterus transitions from actively maintaining quiescence during
pregnancy to an active parturient state. This transition occurs as a result of the accumulation …

Background Preterm birth is now recognized as the primary cause of infant mortality
worldwide. Interplay between hormonal and inflammatory signaling in the uterus modulates …