Functional lung imaging in radiation therapy for lung cancer: A systematic review and meta-analysis

NW Bucknell, N Hardcastle, M Bressel… - Radiotherapy and …, 2018 - Elsevier
Rationale Advanced imaging techniques allow functional information to be derived and
integrated into treatment planning. Methods A systematic review was conducted with the …

Functional image-guided radiotherapy planning for normal lung avoidance

RH Ireland, BA Tahir, JM Wild, CE Lee, MQ Hatton - Clinical Oncology, 2016 - Elsevier
For patients with lung cancer undergoing curative intent radiotherapy, functional lung
imaging can be incorporated into treatment planning to modify the dose distribution within …

A reference dataset for deformable image registration spatial accuracy evaluation using the COPDgene study archive

R Castillo, E Castillo, D Fuentes… - Physics in Medicine …, 2013 - iopscience.iop.org
Landmark point-pairs provide a strategy to assess deformable image registration (DIR)
accuracy in terms of the spatial registration of the underlying anatomy depicted in medical …

Validating and improving CT ventilation imaging by correlating with ventilation 4D‐PET/CT using 68Ga‐labeled nanoparticles

J Kipritidis, S Siva, MS Hofman, J Callahan… - Medical …, 2014 - Wiley Online Library
Purpose: CT ventilation imaging is a novel functional lung imaging modality based on
deformable image registration. The authors present the first validation study of CT ventilation …

Results of a multi-institutional phase 2 clinical trial for 4DCT-ventilation functional avoidance thoracic radiation therapy

Y Vinogradskiy, R Castillo, E Castillo, L Schubert… - International Journal of …, 2022 - Elsevier
Purpose Radiation pneumonitis remains a major limitation in the radiation therapy treatment
of patients with lung cancer. Functional avoidance radiation therapy uses functional imaging …

Hyperpolarized 3He magnetic resonance imaging: comparison with four-dimensional x-ray computed tomography imaging in lung cancer

L Mathew, A Wheatley, R Castillo, E Castillo… - Academic radiology, 2012 - Elsevier
RATIONALE AND OBJECTIVES: Pulmonary functional imaging using four-dimensional x-ray
computed tomographic (4DCT) imaging and hyperpolarized 3He magnetic resonance …

Clinical validation of 4-dimensional computed tomography ventilation with pulmonary function test data

D Brennan, L Schubert, Q Diot, R Castillo… - International Journal of …, 2015 - Elsevier
Purpose A new form of functional imaging has been proposed in the form of 4-dimensional
computed tomography (4DCT) ventilation. Because 4DCTs are acquired as part of routine …

Reproducibility of four-dimensional computed tomography-based lung ventilation imaging

T Yamamoto, S Kabus, J Von Berg, C Lorenz… - Academic radiology, 2012 - Elsevier
RATIONALE AND OBJECTIVES: A novel ventilation imaging method based on four-
dimensional (4D) computed tomography (CT) has been applied to the field of radiation …

Comparison of 4-dimensional computed tomography ventilation with nuclear medicine ventilation-perfusion imaging: a clinical validation study

Y Vinogradskiy, PJ Koo, R Castillo, E Castillo… - International Journal of …, 2014 - Elsevier
Purpose Four-dimensional computed tomography (4DCT) ventilation imaging provides lung
function information for lung cancer patients undergoing radiation therapy. Before 4DCT …

Robust CT ventilation from the integral formulation of the Jacobian

E Castillo, R Castillo, Y Vinogradskiy… - Medical …, 2019 - Wiley Online Library
Computed tomography (CT) derived ventilation algorithms estimate the apparent voxel
volume changes within an inhale/exhale CT image pair. Transformation‐based methods …