Exome sequencing—the targeted sequencing of the subset of the human genome that is
protein coding—is a powerful and cost-effective new tool for dissecting the genetic basis of …

Stem cell research offers great promise for understanding basic mechanisms of human
development and differentiation, as well as the hope for new treatments for diseases such as …

This work has been funded by the Future of Life Institute, as part of the project Towards a
Code of Ethics for Artificial Intelligence Research, awarded under the FLI's 2015 project …

Biobanks and archived data sets collecting samples and data have become crucial engines
of genetic and genomic research. Unresolved, however, is what responsibilities biobanks …

Recent advances in next-generation sequencing technologies have brought a paradigm
shift in how medical researchers investigate both rare and common human disorders. The …

Researchers, institutional review boards (IRBs), participants in human subjects research,
and their families face an important but largely neglected problem—how should incidental …

In January 2009, the National Heart, Lung, and Blood Institute convened a 28-member
multidisciplinary Working Group to update the recommendations of a 2004 National Heart …

Molecular diagnostics, the use of diagnostic testing to understand the molecular
mechanisms of an individual patient's disease, will be pivotal in the delivery of safe and …

Funding bodies have recently introduced a requirement that data sharing must be a
consideration of all funding applications in genomics. As with all new developments this …

Research assessing attitudes toward consent processes for high-throughput genomic-wide
technologies and widespread sharing of data is limited. In order to develop a better …