A layer of mucus covers the surface of all wet epithelia throughout the human body. Mucus is
a hydrogel mainly composed of water, mucins (glycoproteins), DNA, proteins, lipids, and cell …

Chitosan obtained from abundant marine resources has been proven to have a variety of
biological activities. However, due to its poor water solubility, chitosan application is limited …

The use of nitric oxide (NO) is emerging as a promising, novel approach for the treatment of
antibiotic resistant bacteria and biofilm infections. Depending on the concentration, NO can …

Antibiotic resistance in bacteria is a major global threat and a leading cause for healthcare-
related morbidity and mortality. Resistant biofilm infections are particularly difficult to treat …

Pseudomonas aeruginosa is a human pathogen associated with both acute and chronic
infections. While intensively studied, the basic mechanisms enabling the long-term survival …

Chitosan (CS) is the only natural alkaline polysaccharide originated from deacetylation of
chitin that is the main component of shell from marine organisms. It has great potential …

Bacterial biofilms are often difficult to treat and represent the main cause of chronic and
recurrent infections. In this study, we report the synthesis of a novel antimicrobial/antibiofilm …

Asthma is a chronic lung disease affecting millions worldwide. While classically
acknowledged to result from allergen-driven type 2 inflammatory responses leading to IgE …

Nitric oxide (NO) is a broad-spectrum antibacterial agent, making it an attractive alternative
to traditional antibiotics for treating infections. To date, a direct comparison of the …

As a gasotransmitter, nitric oxide (NO) regulates physiological pathways and demonstrates
therapeutic effects such as vascular relaxation, anti-inflammation, antiplatelet …