Exercise and mitochondrial dynamics: keeping in shape with ROS and AMPK
Exercise is a robust stimulus for mitochondrial adaptations in skeletal muscle which
consequently plays a central role in enhancing metabolic health. Despite this, the precise …
consequently plays a central role in enhancing metabolic health. Despite this, the precise …
The MAMs structure and its role in cell death
N Wang, C Wang, H Zhao, Y He, B Lan, L Sun, Y Gao - Cells, 2021 - mdpi.com
The maintenance of cellular homeostasis involves the participation of multiple organelles.
These organelles are associated in space and time, and either cooperate or antagonize …
These organelles are associated in space and time, and either cooperate or antagonize …
[HTML][HTML] State of knowledge on molecular adaptations to exercise in humans: historical perspectives and future directions
For centuries, regular exercise has been acknowledged as a potent stimulus to promote,
maintain, and restore healthy functioning of nearly every physiological system of the human …
maintain, and restore healthy functioning of nearly every physiological system of the human …
Extracellular release of mitochondrial DNA: triggered by cigarette smoke and detected in COPD
L Giordano, AD Gregory, M Pérez Verdaguer, SA Ware… - Cells, 2022 - mdpi.com
Cigarette smoke (CS) is the most common risk factor for chronic obstructive pulmonary
disease (COPD). The present study aimed to elucidate whether mtDNA is released upon CS …
disease (COPD). The present study aimed to elucidate whether mtDNA is released upon CS …
Mitochondrial dysfunctioning and neuroinflammation: Recent highlights on the possible mechanisms involved in Traumatic Brain Injury
Traumatic brain injury (TBI) is the injury to the vasculature of brain while trauma caused by
physical, chemical and biological stimuli. TBI is the leading cause of mortality and morbidity …
physical, chemical and biological stimuli. TBI is the leading cause of mortality and morbidity …
Mitochondrial dynamics: The dynamin superfamily and execution by collusion
R Ramachandran - Seminars in cell & developmental biology, 2018 - Elsevier
Distinct dynamin superfamily GTPases catalyze the constant fission and fusion of the
elaborate mitochondrial networks that navigate the eukaryotic cytoplasm. Long believed to …
elaborate mitochondrial networks that navigate the eukaryotic cytoplasm. Long believed to …
The role of myocardial mitochondrial quality control in heart failure
Z Qiu, Y Wei, Q Song, B Du, H Wang, Y Chu… - Frontiers in …, 2019 - frontiersin.org
At present, the treatment of heart failure has entered the plateau phase, and it is necessary
to thoroughly study the pathogenesis of heart failure and find out the corresponding …
to thoroughly study the pathogenesis of heart failure and find out the corresponding …
TNFR2 stimulation promotes mitochondrial fusion via Stat3-and NF-kB–dependent activation of OPA1 expression
J Nan, H Hu, Y Sun, L Zhu, Y Wang, Z Zhong… - Circulation …, 2017 - Am Heart Assoc
Rationale: Mitochondria are important cellular organelles and play essential roles in
maintaining cell structure and function. Emerging evidence indicates that in addition to …
maintaining cell structure and function. Emerging evidence indicates that in addition to …
The close interconnection between mitochondrial dynamics and mitophagy in cancer
M Bordi, F Nazio, S Campello - Frontiers in oncology, 2017 - frontiersin.org
Recent decades have revealed the shape changes of mitochondria and their regulators to
be main players in a plethora of physiological cell processes. Mitochondria are extremely …
be main players in a plethora of physiological cell processes. Mitochondria are extremely …
Exosome mediated Tom40 delivery protects against hydrogen peroxide-induced oxidative stress by regulating mitochondrial function
Mitochondrial dysfunction is a hallmark of neurodegeneration. The expression level of
Tom40, a crucial mitochondrial membrane protein, is significantly reduced in …
Tom40, a crucial mitochondrial membrane protein, is significantly reduced in …