A systematic review of hepatitis B virus (HBV) drug and vaccine escape mutations in Africa: A call for urgent action

J Mokaya, AL McNaughton, MJ Hadley… - PLoS neglected …, 2018 - journals.plos.org
International sustainable development goals for the elimination of viral hepatitis as a public
health problem by 2030 highlight the pressing need to optimize strategies for prevention …

[HTML][HTML] Hepatocellular carcinoma mouse models: Hepatitis B virus-associated hepatocarcinogenesis and haploinsufficient tumor suppressor genes

YC Teng, ZQ Shen, CH Kao, TF Tsai - World journal of …, 2016 - ncbi.nlm.nih.gov
The multifactorial and multistage pathogenesis of hepatocellular carcinoma (HCC) has
fascinated a wide spectrum of scientists for decades. While a number of major risk factors …

Expression of a hepatitis B virus pre‐S2 deletion mutant in the liver results in hepatomegaly and hepatocellular carcinoma in mice

YC Teng, JC Neo, JC Wu, YF Chen… - The Journal of …, 2017 - Wiley Online Library
Hepatocellular carcinoma (HCC) is the most common form of liver cancer and has a poor
prognosis and a low survival rate; its incidence is on the rise. Hepatitis B virus (HBV) …

Maternal chronic HBV infection would not increase the risk of pregnancy-induced hypertension–results from pregnancy cohort in Liuyang rural China

X Huang, H Tan, X Li, S Zhou, SW Wen, M Luo - PLoS One, 2014 - journals.plos.org
The relationship between maternal HBV (hepatitis B virus) infection and pregnancy-induced
hypertension (PIH) is inconclusive. Few studies have been conducted in rural areas of …

Serum soluble fibrinogen-like protein 2 represents a novel biomarker for differentiation between acute and chronic Egyptian hepatitis B virus-infected patients

M El-Mesery, M El-Mowafy, LF Youssef… - Journal of Interferon & …, 2021 - liebertpub.com
Hepatitis B virus (HBV) infection is considered as one of the most serious public health
problems worldwide including Egypt. Soluble fibrinogen-like protein 2 (sFGL2) is a well …

Health care workers in Pearl River Delta Area of China are not vaccinated adequately against hepatitis B: a retrospective cohort study

YB Zheng, YR Gu, M Zhang, K Wang, Z Huang… - BMC infectious …, 2015 - Springer
Abstract Backgrounds Health-care workers'(HCWs) exposure to bodily fluids puts them at
risk of hepatitis B virus HBV infection. This study investigated HBV vaccination practices and …

Characterization of mutations in hepatitis B virus DNA isolated from Japanese HBsAg-positive blood donors in 2021 and 2022

A Sedohara, K Takahashi, K Arai, K Arizono… - Archives of …, 2024 - Springer
Missense mutations in certain small envelope proteins diminish the efficacy of antibodies.
Consequently, tracking the incidence and types of vaccine-escape mutations (VEMs) was …

Higher detection rates of amino acid substitutions in HBV reverse transcriptase/surface protein overlapping sequence is correlated with lower serum HBV DNA and …

M Su, K Xiang, Y Li, Y Li, J Deng, X Xu, L Yan… - Infection, Genetics and …, 2016 - Elsevier
Abstract Objectives Hepatitis B virus (HBV) subgenotype B2 is prevalent in China and some
other parts of Asia. This study aimed to carry out a subgenotype B2 specific mutation …

Cross-cultural adaptation and psychometric assessment of the liver disease symptom index 2.0 to measure health-related quality of life among Iranian patients with …

M Saffari, SM Alavian, MK Naderi… - Journal of …, 2016 - journals.sagepub.com
Purpose: There are only a few measures to assess quality of life among patients with liver
disorders. The aim of this study was to determine the psychometric properties of the Liver …

[PDF][PDF] Pre-S2 and HBV associated hepatocellular carcinoma

Y Zheng, YY Qian, H Fan - Hepatoma Res, 2018 - f.oaes.cc
Hepatitis B virus (HBV) infection is a primary cause of hepatocellular carcinoma (HCC).
Under selection pressures of host immunity and/or immunoprophylaxis and antiviral …