1, 2, 3-Triazole and its analogues: new surrogates for diazo compounds

M Akter, K Rupa, P Anbarasan - Chemical Reviews, 2022 - ACS Publications
Readily accessible and shelf-stable 1, 2, 3-triazole and its analogues such as pyridotriazole,
triazoloindole, benzotriazole, and thiadiazole exist in equilibrium with their ring-opened …

Medicinal attributes of 1, 2, 3-triazoles: Current developments

D Dheer, V Singh, R Shankar - Bioorganic Chemistry, 2017 - Elsevier
Triazoles are important five-membered heterocyclic scaffold due to their extensive biological
activities. This framework can be readily obtained in good to excellent yields on the …

Beyond click chemistry–supramolecular interactions of 1, 2, 3-triazoles

B Schulze, US Schubert - Chemical Society Reviews, 2014 - pubs.rsc.org
The research on 1, 2, 3-triazoles has been lively and ever-growing since its stimulation by
the advent of click chemistry. The attractiveness of 1H-1, 2, 3-triazoles and their derivatives …

Versatile synthetic platform for 1, 2, 3-triazole chemistry

DP Vala, RM Vala, HM Patel - Acs Omega, 2022 - ACS Publications
1, 2, 3-Triazole scaffolds are not obtained in nature, but they are still intensely investigated
by synthetic chemists in various fields due to their excellent properties and green synthetic …

p-Toluenesulfonic Acid Mediated 1,3-Dipolar Cycloaddition of Nitroolefins with NaN3 for Synthesis of 4-Aryl-NH-1,2,3-triazoles

XJ Quan, ZH Ren, YY Wang, ZH Guan - Organic letters, 2014 - ACS Publications
A p-TsOH-mediated 1, 3-dipolar cycloaddition of nitroolefins and sodium azide for the
synthesis of 4-aryl-NH-1, 2, 3-triazoles has been developed. p-TsOH was discovered as a …

An Organocatalytic Azide–Aldehyde [3+ 2] Cycloaddition: High‐Yielding Regioselective Synthesis of 1, 4‐Disubstituted 1, 2, 3‐Triazoles

DB Ramachary, AB Shashank… - Angewandte Chemie …, 2014 - Wiley Online Library
Abstract An organocatalytic azide–aldehyde [3+ 2] cycloaddition (organo‐click) reaction of a
variety of enolizable aldehydes is reported. The organo‐click reaction is characterized by a …

Recent advances in transition-metal-catalyzed denitrogenative transformations of 1, 2, 3-triazoles and related compounds

P Anbarasan, D Yadagiri, S Rajasekar - Synthesis, 2014 - thieme-connect.com
Suitably substituted electron-deficient 1, 2, 3-triazoles exist in equilibrium with their ring-
opened α-diazoimine tautomers. This phenomenon was used to facilitate the generation of …

A Metal‐Free Three‐Component Reaction for the Regioselective Synthesis of 1, 4, 5‐Trisubstituted 1, 2, 3‐Triazoles

J Thomas, J John, N Parekh, W Dehaen - Angewandte Chemie, 2014 - Wiley Online Library
A metal‐free three‐component reaction to synthesize 1, 4, 5‐trisubstituted 1, 2, 3‐triazoles
from readily available building blocks, such as aldehydes, nitroalkanes, and organic azides …

Sequential one-pot combination of multi-component and multi-catalysis cascade reactions: an emerging technology in organic synthesis

DB Ramachary, S Jain - Organic & biomolecular chemistry, 2011 - pubs.rsc.org
Creating sequential one-pot combinations of multi-component reactions (MCRs) and multi-
catalysis cascade (MCC) reactions is a challenging task that has already emerged as a new …

Ramachary-Bressy-Wang [3+ 2] cycloaddition reaction: Synthesis of fully decorated 1, 2, 3-triazoles as potent anticancer and EGFR inhibitors

M Kumar, SK Nukala, NS Thirukovela… - Journal of Molecular …, 2022 - Elsevier
A general strategy was developed for the synthesis of new fully decorated 1, 2, 3-triazoles
(5a-m & 6a-e) containing coumarine and sulfonyl-benzimidazole from 3-(2-((1-methyl-1H …