PLGA/PLA-based long-acting injectable depot microspheres in clinical use: production and characterization overview for protein/peptide delivery
A Butreddy, RP Gaddam, N Kommineni… - International journal of …, 2021 - mdpi.com
Over the past few decades, long acting injectable (LAI) depots of polylactide-co-glycolide
(PLGA) or polylactic acid (PLA) based microspheres have been developed for controlled …
(PLGA) or polylactic acid (PLA) based microspheres have been developed for controlled …
Poly (lactic acid)/poly (lactic-co-glycolic acid)-based microparticles: An overview
P Blasi - Journal of Pharmaceutical Investigation, 2019 - Springer
Background Poly (glycolic acid), poly (lactic acid) and poly (lactic-co-glycolic acid) were
approved by the United States Food and Drug Administration (FDA) in the 1970s as …
approved by the United States Food and Drug Administration (FDA) in the 1970s as …
The mechanisms of drug release in poly (lactic-co-glycolic acid)-based drug delivery systems—A review
S Fredenberg, M Wahlgren, M Reslow… - International journal of …, 2011 - Elsevier
Abstract Poly (d, l-lactic-co-glycolic acid)(PLGA) is the most frequently used biodegradable
polymer in the controlled release of encapsulated drugs. Understanding the release …
polymer in the controlled release of encapsulated drugs. Understanding the release …
Strategies for encapsulation of small hydrophilic and amphiphilic drugs in PLGA microspheres: state-of-the-art and challenges
Abstract Poly (lactide-co-glycolide)(PLGA) microspheres are efficient delivery systems for
controlled release of low molecular weight drugs as well as therapeutic macromolecules …
controlled release of low molecular weight drugs as well as therapeutic macromolecules …
Principles of encapsulating hydrophobic drugs in PLA/PLGA microparticles
C Wischke, SP Schwendeman - International Journal of pharmaceutics, 2008 - Elsevier
Injectable biodegradable and biocompatible copolymers of lactic and glycolic acid (PLGA)
are an important advanced delivery system for week-to-month controlled release of …
are an important advanced delivery system for week-to-month controlled release of …
Immunized microspheres engineered hydrogel membrane for reprogramming macrophage and mucosal repair
X Wen, K Xi, Y Tang, J Bian, Y Qin, W Xiao, T Pan… - Small, 2023 - Wiley Online Library
The “double‐edged sword” effect of macrophages under the influence of different
microenvironments determines the outcome and prognosis of tissue injury. Accurate and …
microenvironments determines the outcome and prognosis of tissue injury. Accurate and …
Phase behavior of poly (vinylpyrrolidone) containing amorphous solid dispersions in the presence of moisture
ACF Rumondor, PJ Marsac, LA Stanford… - Molecular …, 2009 - ACS Publications
The objective of this study was to investigate the phase behavior of amorphous solid
dispersions composed of a hydrophobic drug and a hydrophilic polymer following exposure …
dispersions composed of a hydrophobic drug and a hydrophilic polymer following exposure …
Evaluation of a degradable shape-memory polymer network as matrix for controlled drug release
Degradable shape-memory polymers are multifunctional materials with broad applicability
for medical devices. They are designed to acquire their therapeutically relevant shape and …
for medical devices. They are designed to acquire their therapeutically relevant shape and …
Phase transition enthalpy measurements of organic and organometallic compounds and ionic liquids. Sublimation, vaporization, and fusion enthalpies from 1880 to …
W Acree, JS Chickos - Journal of Physical and Chemical Reference …, 2017 - pubs.aip.org
This compendium completes a previous report published in 2016 [2016ACR/CHI] on phase
change enthalpies. Paper I of this compendium includes over 6600 organic compounds …
change enthalpies. Paper I of this compendium includes over 6600 organic compounds …
Quantifying drug release from PLGA nanoparticulates
OI Corrigan, X Li - European Journal of Pharmaceutical Sciences, 2009 - Elsevier
The objective of this work was to investigate the mechanism of release of active
pharmaceutical ingredients (APIs) both small molecules (ketoprofen, indomethacin …
pharmaceutical ingredients (APIs) both small molecules (ketoprofen, indomethacin …