MicroRNAs (miRNAs) are a class of short, non-coding RNAs that function post-
transcriptionally to regulate gene expression by binding to particular mRNA targets and …

Hepatocellular carcinoma (HCC) is the fourth leading cause of cancer-related deaths
worldwide. HCC initiation, progression, and therapy failure are all influenced by various …

Abstract Yes-associated protein 1 (YAP1) exerts significant effects in various malignancies.
However, the oncogenic role of YAP1 remains controversial, and the mechanism by which …

Liver cancer is the fourth leading cause of cancer deaths globally, of which hepatocellular
carcinoma (HCC) is the major subtype. Viral hepatitis B and C infections, alcohol abuse, and …

The vascular endothelial growth factor (VEGF) family members, VEGF-A, placenta growth
factor (PlGF), and to a lesser extent VEGF-B, play an essential role in tumor-associated …

Human cancers are characterized by a number of hallmarks, including sustained
proliferative signaling, evasion of growth suppressors, activated invasion and metastasis …

Both acute and chronic liver toxicity represents a major global health burden and an
important cause of morbidity and lethality worldwide. Despite epochal progress in the …

Osteosarcoma is the most common primary malignant bone tumor in children and
adolescents, with highly aggressive behavior and early systemic metastasis. The survival …

Angiogenesis is a multi-stage process of new blood vessel development from pre-existing
vessels toward an angiogenic stimulus. The process is essential for tissue maintenance and …

Hepatocellular carcinoma (HCC) is one of the most common cancers, leading to the second
cancer-related death in the global. Although the treatment of HCC has greatly improved over …