[HTML][HTML] Liver fibrosis

MM Aydın, KC Akçalı - The Turkish Journal of Gastroenterology, 2018 - ncbi.nlm.nih.gov
Liver fibrosis is a wound-healing response generated against an insult to the liver that
causes liver injury. It has the potential to progress into cirrhosis, and if not prevented, it may …

Experimental models of liver fibrosis

S Crespo Yanguas, B Cogliati, J Willebrords… - Archives of …, 2016 - Springer
Hepatic fibrosis is a wound healing response to insults and as such affects the entire world
population. In industrialized countries, the main causes of liver fibrosis include alcohol …

Mdm2 phosphorylation by Akt regulates the p53 response to oxidative stress to promote cell proliferation and tumorigenesis

L Chibaya, B Karim, H Zhang… - Proceedings of the …, 2021 - National Acad Sciences
We have shown previously that phosphorylation of Mdm2 by ATM and c-Abl regulates Mdm2-
p53 signaling and alters the effects of DNA damage in mice, including bone marrow failure …

HDL and LDL: potential new players in breast cancer development

L Cedó, ST Reddy, E Mato, F Blanco-Vaca… - Journal of clinical …, 2019 - mdpi.com
Breast cancer is the most prevalent cancer and primary cause of cancer-related mortality in
women. The identification of risk factors can improve prevention of cancer, and obesity and …

Oxidized low-density lipoprotein links hypercholesterolemia and bladder cancer aggressiveness by promoting cancer stemness

L Yang, J Sun, M Li, Y Long, D Zhang, H Guo, R Huang… - Cancer research, 2021 - AACR
Hypercholesterolemia is a prevalent metabolic disorder that has been implicated in the
development of steroid-targeted cancers. However, the link between hypercholesterolemia …

Chemoprevention of liver cancer by plant polyphenols

D Stagos, GD Amoutzias, A Matakos, A Spyrou… - Food and Chemical …, 2012 - Elsevier
Primary liver cancer or hepatocellular carcinoma (HCC) is one of the most frequent tumors
representing the fifth commonest malignancy worldwide and the third cause of mortality from …

Resveratrol-mediated chemoprevention of diethylnitrosamine-initiated hepatocarcinogenesis: inhibition of cell proliferation and induction of apoptosis

A Bishayee, N Dhir - Chemico-biological interactions, 2009 - Elsevier
Hepatocellular carcinoma (HCC) is one of the most common cancers and lethal diseases. In
view of the limited treatment and a grave prognosis of liver cancer, preventive control has …

Pomegranate-mediated chemoprevention of experimental hepatocarcinogenesis involves Nrf2-regulated antioxidant mechanisms

A Bishayee, D Bhatia, RJ Thoppil, AS Darvesh… - …, 2011 - academic.oup.com
Hepatocellular carcinoma (HCC), one of the most prevalent and lethal cancers, has shown
an alarming rise in the USA. Without effective therapy for HCC, novel chemopreventive …

Inhibition of reactive oxygen species and pre-neoplastic lesions by quercetin through an antioxidant defense mechanism

VR Vásquez-Garzón, J Arellanes-Robledo… - Free radical …, 2009 - Taylor & Francis
There is a correlation between oxidative stress generated by diethylnitrosamine (DEN)
metabolism and liver cancer development. Quercetin is a flavonoid with anti-carcinogenic …

Chemopreventive and therapeutic potential of tea polyphenols in hepatocellular cancer

AS Darvesh, A Bishayee - Nutrition and cancer, 2013 - Taylor & Francis
The prophylactic and therapeutic properties of tea have been attributed to green tea
catechins and black tea theaflavins besides several other polyphenolic compounds. Tea …