Background: Common cancers develop through a multistep process often including
inherited susceptibility. Collaboration among multiple institutions, and funding from multiple …

To identify new susceptibility loci to lung cancer among diverse populations, we performed
cross-ancestry genome-wide association studies in European, East Asian and African …

Although several lung cancer susceptibility loci have been identified, much of the heritability
for lung cancer remains unexplained. Here 14,803 cases and 12,262 controls of European …

To identify common alleles associated with different histotypes of epithelial ovarian cancer
(EOC), we pooled data from multiple genome-wide genotyping projects totaling 25,509 EOC …

Most common breast cancer susceptibility variants have been identified through genome-
wide association studies (GWAS) of predominantly estrogen receptor (ER)-positive disease …

Genome-wide association studies (GWAS) have transformed our understanding of glioma
susceptibility, but individual studies have had limited power to identify risk loci. We …

Single nucleotide polymorphisms (SNPs) are the most abundant type of genomic variation
and the most accessible to genotype in large cohorts. However, they individually explain a …

Genetic models for cancer have been evaluated using almost exclusively European data,
which could exacerbate health disparities. A polygenic hazard score (PHS1) is associated …

Incidence of glioma is approximately 50% higher in males. Previous analyses have
examined exposures related to sex hormones in women as potential protective factors for …

To identify genetic variants for risk of squamous cell carcinoma of the head and neck
(SCCHN), we conducted a two-phase genome-wide association study consisting of …