Benefits of zebrafish xenograft models in cancer research
X Chen, Y Li, T Yao, R Jia - Frontiers in Cell and Developmental …, 2021 - frontiersin.org
As a promising in vivo tool for cancer research, zebrafish have been widely applied in
various tumor studies. The zebrafish xenograft model is a low-cost, high-throughput tool for …
various tumor studies. The zebrafish xenograft model is a low-cost, high-throughput tool for …
Preclinical models of glioblastoma: Limitations of current models and the promise of new developments
P Liu, S Griffiths, D Veljanoski… - Expert Reviews in …, 2021 - cambridge.org
Glioblastoma (GBM) is the most common and aggressive primary brain tumour, yet little
progress has been made towards providing better treatment options for patients diagnosed …
progress has been made towards providing better treatment options for patients diagnosed …
[HTML][HTML] Mesenchymal stem cells differentially affect the invasion of distinct glioblastoma cell lines
Glioblastoma multiforme are an aggressive form of brain tumors that are characterized by
distinct invasion of single glioblastoma cells, which infiltrate the brain parenchyma. This …
distinct invasion of single glioblastoma cells, which infiltrate the brain parenchyma. This …
Single‐cell profiling and zebrafish avatars reveal LGALS1 as immunomodulating target in glioblastoma
Glioblastoma (GBM) remains the most malignant primary brain tumor, with a median survival
rarely exceeding 2 years. Tumor heterogeneity and an immunosuppressive …
rarely exceeding 2 years. Tumor heterogeneity and an immunosuppressive …
TLR4 signaling drives mesenchymal stromal cells commitment to promote tumor microenvironment transformation in multiple myeloma
C Giallongo, D Tibullo, G Camiolo, NL Parrinello… - Cell death & …, 2019 - nature.com
Inflammation represents a key feature and hallmark of tumor microenvironment playing a
major role in the interaction with mesenchymal stromal cells (MSC) in cancer progression …
major role in the interaction with mesenchymal stromal cells (MSC) in cancer progression …
TRIM28 selective nanobody reduces glioblastoma stem cell invasion
A Porčnik, M Novak, B Breznik, B Majc, B Hrastar… - Molecules, 2021 - mdpi.com
Glioblastoma (GB), is the most common and aggressive malignant primary brain tumour in
adults. Intra-and inter-tumour heterogeneity, infiltrative GB cell invasion and presence of …
adults. Intra-and inter-tumour heterogeneity, infiltrative GB cell invasion and presence of …
Identify a blood-brain barrier penetrating drug-TNB using zebrafish orthotopic glioblastoma xenograft model
A Zeng, T Ye, D Cao, X Huang, Y Yang, X Chen… - Scientific reports, 2017 - nature.com
The blood–brain barrier (BBB) is necessary for maintaining brain homeostasis, but it also
represents a major challenge for drug delivery to the brain tumors. A suitable in vivo …
represents a major challenge for drug delivery to the brain tumors. A suitable in vivo …
Cellular and molecular mechanisms underlying glioblastoma and zebrafish models for the discovery of new treatments
P Reimunde, A Pensado-López, M Carreira Crende… - Cancers, 2021 - mdpi.com
Simple Summary Glioblastoma (GBM) is one of the greatest challenges facing neuro-
oncology today. Current treatments are far from satisfactory and, given the poor prognosis of …
oncology today. Current treatments are far from satisfactory and, given the poor prognosis of …
Three-dimensional imaging in stem cell-based researches
F Nowzari, H Wang, A Khoradmehr… - Frontiers in Veterinary …, 2021 - frontiersin.org
Stem cells have an important role in regenerative therapies, developmental biology studies
and drug screening. Basic and translational research in stem cell technology needs more …
and drug screening. Basic and translational research in stem cell technology needs more …
Zebrafish in translational cancer research: insight into leukemia, melanoma, glioma and endocrine tumor biology
AI Idilli, F Precazzini, MC Mione, V Anelli - Genes, 2017 - mdpi.com
Over the past 15 years, zebrafish have emerged as a powerful tool for studying human
cancers. Transgenic techniques have been employed to model different types of tumors …
cancers. Transgenic techniques have been employed to model different types of tumors …