Synthetic and medicinal perspective of quinolines as antiviral agents

R Kaur, K Kumar - European Journal of Medicinal Chemistry, 2021 - Elsevier
In current scenario, various heterocycles have come up exhibiting crucial role in various
medicinal agents which are valuable for mankind. Out of diverse range of heterocycle …

Understanding metal synergy in heterodinuclear catalysts for the copolymerization of CO2 and epoxides

AC Deacy, AFR Kilpatrick, A Regoutz, CK Williams - Nature chemistry, 2020 - nature.com
Carbon dioxide and epoxide copolymerization is an industrially relevant means to valorize
waste and improve sustainability in polymer manufacturing. Given the value of the polymer …

Anthranils: versatile building blocks in the construction of C–N bonds and N-heterocycles

Y Gao, J Nie, Y Huo, XQ Hu - Organic Chemistry Frontiers, 2020 - pubs.rsc.org
Anthranils are readily available and have recently emerged as versatile building blocks in
the assembly of various C–N bonds and medicinally active heterocyclic systems. A great …

Enantioselective Reductive (Hetero)Arylation of Cyclic N‐Sulfonyl Imines by Cobalt Catalysis

J Xiao, M Wang, X Yin, S Yang, P Gu, X Lv… - Angewandte …, 2023 - Wiley Online Library
Transition‐metal‐catalyzed enantioselective addition of aryl organometallic reagents to
imines has emerged as one of the most powerful tools for the formation of optically active …

Pd‐Catalyzed Dearomatization of Anthranils with Vinylcyclopropanes by [4+ 3] Cyclization Reaction

Q Cheng, JH Xie, YC Weng… - Angewandte Chemie …, 2019 - Wiley Online Library
Dearomatization of anthranils with vinylcyclopropanes (VCPs) by Pd‐catalyzed [4+ 3]
cyclization reaction has been realized. In the presence of a catalytic amount of borane as an …

[HTML][HTML] Organozinc pivalates for cobalt-catalyzed difluoroalkylarylation of alkenes

X Cheng, X Liu, S Wang, Y Hu, B Hu, A Lei… - Nature …, 2021 - nature.com
Installation of fluorine into pharmaceutically relevant molecules plays a vital role in their
properties of biology or medicinal chemistry. Direct difunctionalization of alkenes and 1, 3 …

NiH-Catalyzed Hydroamination/Cyclization Cascade: Rapid Access to Quinolines

Y Gao, S Yang, Y Huo, Q Chen, X Li, XQ Hu - ACS Catalysis, 2021 - ACS Publications
Despite the significant success of metal-H-catalyzed hydroamination methodologies,
considerable limitations still exist in the selective hydroamination of alkynes, especially for …

Rh-Catalyzed C–H Amination/Annulation of Acrylic Acids and Anthranils by Using− COOH as a Deciduous Directing Group: An Access to Diverse Quinolines

Y Gao, J Nie, Y Li, X Li, Q Chen, Y Huo, XQ Hu - Organic letters, 2020 - ACS Publications
A method for the synthesis of diverse polysubstituted quinolines from readily available
acrylic acids and anthranils has been developed. The weakly coordinating–COOH directing …

Copper-catalyzed annulation or homocoupling of sulfoxonium ylides: synthesis of 2, 3-diaroylquinolines or α, α, β-tricarbonyl sulfoxonium ylides

S Zhu, K Shi, H Zhu, ZK Jia, XF Xia, D Wang… - Organic letters, 2020 - ACS Publications
An unprecedented copper-catalyzed reaction of sulfoxonium ylides and anthranils is
reported that enables an easy access to 2, 3-diaroylquinolines through a [4+ 1+ 1] …

Transition Metal‐Mediated Functionalization of Isoxazoles: A Review

S Madhavan, SK Keshri, M Kapur - Asian Journal of Organic …, 2021 - Wiley Online Library
Isoxazoles are an important class of heterocycles with nitrogen and oxygen in a 1, 2‐
relationship. They find wide applications in synthetic organic chemistry and are part of …