Abstract Organs-on-chips (OoCs) are systems containing engineered or natural miniature
tissues grown inside microfluidic chips. To better mimic human physiology, the chips are …

The four-dimensional nucleome (4DN) consortium studies the architecture of the genome
and the nucleus in space and time. We summarize progress by the consortium and highlight …

Neuromuscular networks assemble during early human embryonic development and are
essential for the control of body movement. Previous neuromuscular junction modeling …

Alzheimer's disease (AD) is a progressive neurodegenerative disease with no cure. Huge
efforts have been made to develop anti‐AD drugs in the past decades. However, all drug …

Acoustic tweezers can control target movement through the momentum interaction between
an acoustic wave and an object. This technology has advantages over optical tweezers for …

Life expectancy has increased by three decades since the mid-twentieth century. Parallel
healthspan expansion has however not followed, largely impeded by the pandemic of …

Abstract mRNA formulated with lipid nanoparticles is a transformative technology that has
enabled the rapid development and administration of billions of coronavirus disease 2019 …

Research in cell biology greatly relies on cell-based in vitro assays and models that facilitate
the investigation and understanding of specific biological events and processes under …

Pluripotent stem cells (PSCs) hold great potential for novel therapeutic approaches to
regenerate or replace functionally impaired tissues. Since the introduction of the induced …

Cardiovascular disease remains the leading cause of morbidity and mortality in the
developed world. In recent decades, extraordinary effort has been devoted to defining the …