Pluripotent stem cells from domesticated mammals
This review deals with the latest advances in the study of embryonic stem cells (ESC) and
induced pluripotent stem cells (iPSC) from domesticated species, with a focus on pigs, cattle …
induced pluripotent stem cells (iPSC) from domesticated species, with a focus on pigs, cattle …
[PDF][PDF] Beyond the mouse: Non-rodent animal models for study of early mammalian development and biomedical research
The preimplantation development of mammals generally follows the same plan. It starts with
the formation of a totipotent zygote, and through consecutive cleavage divisions and …
the formation of a totipotent zygote, and through consecutive cleavage divisions and …
Preclinical derivation and imaging of autologously transplanted canine induced pluripotent stem cells
Derivation of patient-specific induced pluripotent stem cells (iPSCs) opens a new avenue for
future applications of regenerative medicine. However, before iPSCs can be used in a …
future applications of regenerative medicine. However, before iPSCs can be used in a …
Safety and efficacy of the mesenchymal stem cell in feline eosinophilic keratitis treatment
AJ Villatoro, S Claros, V Fernández… - BMC veterinary …, 2018 - Springer
Background Feline eosinophilic keratitis (FEK) is a chronic keratopathy caused by a
suspected immune mediated response to an unknown antigenic stimulus. The purpose of …
suspected immune mediated response to an unknown antigenic stimulus. The purpose of …
From “ES-like” cells to induced pluripotent stem cells: a historical perspective in domestic animals
S Koh, JA Piedrahita - Theriogenology, 2014 - Elsevier
Pluripotent stem cells such as embryonic stem cells (ESCs) and induced pluripotent stem
cells (iPSCs) provide great potential as cell sources for gene editing to generate genetically …
cells (iPSCs) provide great potential as cell sources for gene editing to generate genetically …
Generation and characterization of LIF-dependent canine induced pluripotent stem cells from adult dermal fibroblasts
DJ Whitworth, DA Ovchinnikov… - Stem cells and …, 2012 - liebertpub.com
Dogs provide a more clinically relevant model of human disease than rodents, particularly
with respect to hereditary diseases. Thus, the availability of canine stem cells will greatly …
with respect to hereditary diseases. Thus, the availability of canine stem cells will greatly …
Stem cell therapies for treating osteoarthritis: prescient or premature?
DJ Whitworth, TA Banks - The Veterinary Journal, 2014 - Elsevier
There has been unprecedented interest in recent years in the use of stem cells as therapy
for an array of diseases in companion animals. Stem cells have already been deployed …
for an array of diseases in companion animals. Stem cells have already been deployed …
Derivation of canine induced pluripotent stem cells
Contents Dogs and humans have many inherited genetic diseases in common and
conditions that are increasingly prevalent in humans also occur naturally in dogs. The use of …
conditions that are increasingly prevalent in humans also occur naturally in dogs. The use of …
Cell therapy in veterinary medicine as a proof-of-concept for human therapies: perspectives from the North American Veterinary Regenerative Medicine Association
In the past decade, the potential to translate scientific discoveries in the area of regenerative
therapeutics in veterinary species to novel, effective human therapies has gained interest …
therapeutics in veterinary species to novel, effective human therapies has gained interest …
Growth requirements and chromosomal instability of induced pluripotent stem cells generated from adult canine fibroblasts
In mice and humans, it has been shown that embryonic and adult fibroblasts can be
reprogrammed into pluripotency by introducing 4 transcription factors, Oct3/4, Klf4, Sox2 …
reprogrammed into pluripotency by introducing 4 transcription factors, Oct3/4, Klf4, Sox2 …