Photocatalytic late-stage C–H functionalization

P Bellotti, HM Huang, T Faber, F Glorius - Chemical Reviews, 2023 - ACS Publications
The emergence of modern photocatalysis, characterized by mildness and selectivity, has
significantly spurred innovative late-stage C–H functionalization approaches that make use …

Radical C(sp3)–H functionalization and cross-coupling reactions

DL Golden, SE Suh, SS Stahl - Nature Reviews Chemistry, 2022 - nature.com
C–H functionalization reactions are playing an increasing role in the preparation and
modification of complex organic molecules, including pharmaceuticals, agrochemicals and …

Photoredox-catalyzed C–H functionalization reactions

N Holmberg-Douglas, DA Nicewicz - Chemical reviews, 2021 - ACS Publications
The fields of C–H functionalization and photoredox catalysis have garnered enormous
interest and utility in the past several decades. Many different scientific disciplines have …

[PDF][PDF] Photoinduced intermolecular hydrogen atom transfer reactions in organic synthesis

H Cao, X Tang, H Tang, Y Yuan, J Wu - Chem Catalysis, 2021 - cell.com
Hydrogen-atom transfer (HAT) provides straightforward methods to generate open-shell
radical intermediates from RH (R= C, Si, etc.) bonds and offers unique opportunities for …

Metallaphotoredox catalysis for sp 3 C–H functionalizations through hydrogen atom transfer (HAT)

J Zhang, M Rueping - Chemical Society Reviews, 2023 - pubs.rsc.org
In recent years, the integration of photocatalytic hydrogen atom transfer (HAT) with transition
metal catalysis has emerged as a formidable strategy for the construction of C (sp3)–carbon …

The persistent radical effect in organic synthesis

D Leifert, A Studer - Angewandte Chemie International Edition, 2020 - Wiley Online Library
Radical–radical couplings are mostly nearly diffusion‐controlled processes. Therefore, the
selective cross‐coupling of two different radicals is challenging and not a synthetically …

Strategies and Mechanisms of First-Row Transition Metal-Regulated Radical C–H Functionalization

X Wang, J He, YN Wang, Z Zhao, K Jiang… - Chemical …, 2024 - ACS Publications
Radical C–H functionalization represents a useful means of streamlining synthetic routes by
avoiding substrate preactivation and allowing access to target molecules in fewer steps. The …

Synthetic and Mechanistic Implications of Chlorine Photoelimination in Nickel/Photoredox C(sp3)–H Cross-Coupling

SK Kariofillis, AG Doyle - Accounts of chemical research, 2021 - ACS Publications
Conspectus In recent years, the development of light-driven reactions has contributed
numerous advances in synthetic organic chemistry. A particularly active research area …

Recent advances in photoredox and nickel dual-catalyzed cascade reactions: pushing the boundaries of complexity

C Zhu, H Yue, L Chu, M Rueping - Chemical science, 2020 - pubs.rsc.org
Cascade reactions that produce multiple chemical bonds in one synthetic operation are
important in the efficient construction of complex molecules. In addition, photoredox and …

Photocatalytic hydrogen atom transfer: the philosopher's stone for late-stage functionalization?

L Capaldo, LL Quadri, D Ravelli - Green Chemistry, 2020 - pubs.rsc.org
An overview about the potentialities of photocatalytic Hydrogen Atom Transfer (HAT) for the
Late-Stage Functionalization (LSF) of complex molecules is offered. The examined …