Cancer is a leading cause of morbidity and mortality worldwide. Apoptosis is a process of
programmed cell death and it plays a vital role in human development and tissue …

Cancer remains one of the leading causes of death worldwide, especially lung cancer.
Chemotherapeutic drugs are commonly used for lung cancer treatment; nonetheless …

Simple Summary The treatment of colorectal cancer (CRC) is still a major challenge, and the
manipulation of pyroptosis has become a novel therapeutic strategy for cancers. Gambogic …

Objectives To investigate the protective effects of Shexiang Tongxin Dropping Pill
(麝香通心滴丸, STP) on Na 2 S 2 O 4-induced hypoxia-reoxygenation injury in …

Gambogic acid (GA) is a naturally derived potent anticancer agent with extremely poor
aqueous solubility. In the present study, positively charged PEGylated liposomal formulation …

The emergence of chemoresistance is a major limitation of colorectal cancer (CRC)
therapies and novel biologically based therapies are urgently needed. Natural products …

Clinical radiation therapy (RT) is often hindered by the low radiation energy absorption
coefficient and the hypoxic features of tumor tissues. Among the tremendous efforts devoted …

Gambogic acid (GA), the main active component of gamboge resin, has potent antitumor
activity both in vivo and in vitro. However, the underlying molecular mechanisms remain …

Defects in apoptosis are common phenomena in many types of cancer and are also a critical
step in tumorigenesis. Targeting the apoptotic pathway has been considered an intriguing …

Mitochondria are important targets for the intracellular delivery of drugs and DNA. For
mitochondria-targeted delivery, a mitochondriotropic molecule, triphenylphosphonium …