[HTML][HTML] The world federation of ADHD international consensus statement: 208 evidence-based conclusions about the disorder

SV Faraone, T Banaschewski, D Coghill… - Neuroscience & …, 2021 - Elsevier
Background Misconceptions about ADHD stigmatize affected people, reduce credibility of
providers, and prevent/delay treatment. To challenge misconceptions, we curated findings …

[PDF][PDF] Neurodevelopment of the association cortices: Patterns, mechanisms, and implications for psychopathology

VJ Sydnor, B Larsen, DS Bassett, A Alexander-Bloch… - Neuron, 2021 - cell.com
The human brain undergoes a prolonged period of cortical development that spans multiple
decades. During childhood and adolescence, cortical development progresses from lower …

A cross-population atlas of genetic associations for 220 human phenotypes

S Sakaue, M Kanai, Y Tanigawa, J Karjalainen… - Nature …, 2021 - nature.com
Current genome-wide association studies do not yet capture sufficient diversity in
populations and scope of phenotypes. To expand an atlas of genetic associations in non …

Maternal immune activation and neuroinflammation in human neurodevelopmental disorders

VX Han, S Patel, HF Jones, RC Dale - Nature Reviews Neurology, 2021 - nature.com
Maternal health during pregnancy plays a major role in shaping health and disease risks in
the offspring. The maternal immune activation hypothesis proposes that inflammatory …

Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction

R Karlsson Linnér, TT Mallard, PB Barr… - Nature …, 2021 - nature.com
Behaviors and disorders related to self-regulation, such as substance use, antisocial
behavior and attention-deficit/hyperactivity disorder, are collectively referred to as …

Longitudinal assessment of mental health disorders and comorbidities across 4 decades among participants in the Dunedin birth cohort study

A Caspi, RM Houts, A Ambler, A Danese… - JAMA network …, 2020 - jamanetwork.com
Importance Mental health professionals typically encounter patients at 1 point in patients'
lives. This cross-sectional window understandably fosters focus on the current presenting …

The multiplex model of the genetics of Alzheimer's disease

R Sims, M Hill, J Williams - Nature neuroscience, 2020 - nature.com
Genes play a strong role in Alzheimer's disease (AD), with late-onset AD showing heritability
of 58–79% and early-onset AD showing over 90%. Genetic association provides a robust …

[HTML][HTML] Maternal acute and chronic inflammation in pregnancy is associated with common neurodevelopmental disorders: a systematic review

VX Han, S Patel, HF Jones, TC Nielsen… - Translational …, 2021 - nature.com
Inflammation is increasingly recognized as a cause or consequence of common problems of
humanity including obesity, stress, depression, pollution and disease states such as …

Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions

DM Howard, MJ Adams, TK Clarke, JD Hafferty… - Nature …, 2019 - nature.com
Major depression is a debilitating psychiatric illness that is typically associated with low
mood and anhedonia. Depression has a heritable component that has remained difficult to …

[HTML][HTML] Shared mechanisms across the major psychiatric and neurodegenerative diseases

TS Wingo, Y Liu, ES Gerasimov, SM Vattathil… - Nature …, 2022 - nature.com
Several common psychiatric and neurodegenerative diseases share epidemiologic risk;
however, whether they share pathophysiology is unclear and is the focus of our …