Potent candidates for Targeted Auger Therapy: Production and radiochemical considerations
D Filosofov, E Kurakina, V Radchenko - Nuclear Medicine and Biology, 2021 - Elsevier
Abstract Targeted Auger Therapy represents great potential for the therapy of diseases
which require a high degree of selectivity on the cellular level (eg for therapy of metastatic …
which require a high degree of selectivity on the cellular level (eg for therapy of metastatic …
The use of the macrocyclic chelator DOTA in radiochemical separations
Radiometals play an important role in the diagnosis of physiological processes in vivo by
means of imaging technologies, but also increasingly contribute to the treatment of diseases …
means of imaging technologies, but also increasingly contribute to the treatment of diseases …
Capturing an elusive but critical element: Natural protein enables actinium chemistry
GJP Deblonde, JA Mattocks, Z Dong, PT Wooddy… - Science …, 2021 - science.org
Actinium-based therapies could revolutionize cancer medicine but remain tantalizing due to
the difficulties in studying and limited knowledge of Ac chemistry. Current efforts focus on …
the difficulties in studying and limited knowledge of Ac chemistry. Current efforts focus on …
Including and declaring structural fluctuations in the study of Lanthanide (III) coordination chemistry in solution
LG Nielsen, TJ Sørensen - Inorganic chemistry, 2019 - ACS Publications
The physicochemical properties of lanthanide (III) ions are directly linked to the structure of
the surrounding ligands. Rapid ligand exchange prohibits direct structure–property …
the surrounding ligands. Rapid ligand exchange prohibits direct structure–property …
H3nota Derivatives Possessing Picolyl and Picolinate Pendants for Ga3+ Coordination and 67Ga3+ Radiolabeling
A Marlin, A Koller, E Madarasi, M Cordier… - Inorganic …, 2023 - ACS Publications
We synthesized, thanks to the regiospecific N-functionalization using an orthoamide
intermediate, two 1, 4, 7-triazacyclononane derivatives containing an acetate arm and either …
intermediate, two 1, 4, 7-triazacyclononane derivatives containing an acetate arm and either …
Chelation with a twist: a bifunctional chelator to enable room temperature radiolabeling and targeted PET imaging with scandium-44
BA Vaughn, SH Ahn, E Aluicio-Sarduy, J Devaraj… - Chemical …, 2020 - pubs.rsc.org
Scandium-44 has emerged as an attractive, novel PET radioisotope with ideal emission
properties and half-life (t1/2= 3.97 h, Emean β+= 632 keV) well matched to the …
properties and half-life (t1/2= 3.97 h, Emean β+= 632 keV) well matched to the …
Production and use of the first-row transition metal PET radionuclides 43, 44Sc, 52Mn, and 45Ti
With the increasing focus on a more personalized approach to medicine using imaging
techniques to select patients for targeted treatment or theranostic strategies, interest in the …
techniques to select patients for targeted treatment or theranostic strategies, interest in the …
Novel theranostic agent for PET imaging and targeted radiopharmaceutical therapy of tumour-infiltrating immune cells in glioma
A Foster, S Nigam, DS Tatum, I Raphael, J Xu… - …, 2021 - thelancet.com
Background Malignant gliomas are deadly tumours with few therapeutic options. Although
immunotherapy may be a promising therapeutic strategy for treating gliomas, a significant …
immunotherapy may be a promising therapeutic strategy for treating gliomas, a significant …
Development and Validation of an Analytical HPLC Method to Assess Chemical and Radiochemical Purity of [68Ga]Ga-NODAGA-Exendin-4 Produced by a Fully …
S Migliari, A Sammartano, M Boss, M Gotthardt… - Molecules, 2022 - mdpi.com
Background: Glucagon-like peptide 1 receptor (GLP-1R) is preferentially expressed in
pancreatic islets, especially in β-cells, and highly expressed in human insulinomas and …
pancreatic islets, especially in β-cells, and highly expressed in human insulinomas and …
Towards 213 Bi alpha-therapeutics and beyond: unravelling the foundations of efficient Bi III complexation by DOTP
D Horváth, F Travagin, N Guidolin… - Inorganic Chemistry …, 2021 - pubs.rsc.org
Bismuth isotopes are attracting increasing attention for their potential applications in
diagnostics and therapy. The emerging use of 213Bi in targeted α-therapy (TAT) is a …
diagnostics and therapy. The emerging use of 213Bi in targeted α-therapy (TAT) is a …