OBJECTIVES: In 2015, the Selecting Therapeutic Targets in Inflammatory Bowel Disease
(STRIDE) program proposed shifting the therapeutic focus on ulcerative colitis (UC) toward …

Background & Aims Clinical remission, defined by a composite of patient reported outcomes
and Mayo endoscopy subscore (MES) 0 or 1 is a recommended treatment target in patients …

Histological remission is evolving as an important treatment target in UC. We aimed to
develop a simple histological index, aligned to endoscopy, correlated with clinical outcomes …

Currently, the main targets of drug therapy for ulcerative colitis [UC] are endoscopic and
clinical remission. However, there is active discussion about the additional advantages of …

Ulcerative colitis (UC) is a chronic disease that can present at various stages of disease
activity and severity. Depending on disease activity at any moment and the overall severity …

Background Endoscopic remission is a recognized therapeutic endpoint in inflammatory
bowel disease (IBD; Crohn's disease (CD), ulcerative colitis (UC)). The impact of persistent …

Abstract Background and Aims This analysis examined the long-term safety and efficacy of
ozanimod in patients with moderately to severely active ulcerative colitis [UC] with≥ 4 years …

Background and Aims Assessment of disease activity is essential for developing and
determining appropriate therapy in patients with ulcerative colitis (UC). Validated clinical …

Objectives To study the role of faecal microbiota transplantation [FMT] in maintenance of
remission in ulcerative colitis [UC]. Methods In this pilot study, patients with UC in clinical …

The concept of disease clearance has been proposed as a potential target in ulcerative
colitis (UC). We conducted a systematic review to investigate the role of disease clearance …