Cellular senescence, first described in vitro in 1961, has become a focus for biotech
companies that target it to ameliorate a variety of human conditions. Eminently characterized …

The applications of modern artificial intelligence (AI) algorithms within the field of aging
research offer tremendous opportunities. Aging is an almost universal unifying feature …

Short telomeres trigger age-related pathologies and shorter lifespans in mice and humans.
In the past, we generated mouse embryonic (ES) cells with longer telomeres than normal …

Non-small cell lung cancer (NSCLC) is a leading cause of cancer death. Tumor progression
depends on interactions of cancer cells with the tumor microenvironment. Here, we find …

Short/dysfunctional telomeres are at the origin of idiopathic pulmonary fibrosis (IPF) in
patients mutant for telomere maintenance genes. However, it remains unknown whether …

Neurodegenerative diseases associated with old age such as Alzheimer's disease present
major problems for society, and they currently have no cure. The telomere protective caps at …

Telomeres are the protective end caps of chromosomes and shorten with every cell division.
Short telomeres are associated with older age and adverse lifestyle factors. Leucocyte …

Extrinsic and intrinsic factors contribute to skin aging; nonetheless, they are intertwined.
Moreover, intrinsic skin aging mirrors age-related declines in the entire human body's …

Aging is an unavoidable process, leading to cell senescence due to physiochemical
changes in an organism. Anti-aging remedies have always been of great interest since …

Exercise transiently impacts the expression, regulation, and activity of TERT/telomerase to
maintain telomeres and protect the genome from insults. By protecting the telomeres …