The recent unraveling of structures of genes for the gonadotropin subunits and gonadotropin
receptors has provided reproductive endocrinologists with new tools to study normal and …

The genetic mechanisms underlying functional hyperandrogenism and the polycystic ovary
syndrome (PCOS) remain largely unknown. Given the large number of genetic variants …

LH and chorionic gonadotropin (CG) are glycoproteins fundamental to sexual development
and reproduction. Because they act on the same receptor (LHCGR), the general consensus …

Objective: To review the evidence that polycystic ovary syndrome is a genetic disease.
Design: Review of published literature. Results: The existing literature provides a strong …

The polycystic appearance of the ovary is the distinguishing characteristic of polycystic ovary
syndrome (PCOS) but there is a wide range of other clinical and biochemical features, eg …

BACKGROUND The identification of polymorphisms associated with a disease can help to
elucidate its pathogenesis, and this knowledge can be used to improve prognosis for …

BACKGROUND: Oral contraceptive pills (OC) are usually the first choice of treatment for
polycystic ovarian syndrome (PCOS), when fertility is not desired. However, they do not …

Polycystic ovary syndrome (PCOS) is a heterogeneous disorder. There is evidence for a
genetic component in PCOS based on familial clustering of cases. The majority of the …

Polycystic ovary syndrome (PCOS) is a syndrome involving defects in primary cellular
control mechanisms that result in the expression of chronic anovulation and …

Altered folliculogenesis and reproductive anomalies in polycystic ovary syndrome (PCOS)
suggest that variations of genes involved in folliculogenesis might influence …