The fine line between human health and disease can be driven by the interplay between
host and microbial factors. This “metagenome” regulates cancer initiation, progression, and …

Pseudomonas aeruginosa can efficiently adapt to changing environmental conditions due to
its ubiquitous nature, intrinsic/acquired/adaptive resistance mechanisms, high metabolic …

Hepatic encephalopathy (HE) can cause major morbidity despite standard of care (SOC;
rifaximin/lactulose). Fecal microbial transplant (FMT) enemas postantibiotics are safe, but …

Rationale: In lung cancer, upregulation of the PI3K (phosphoinositide 3-kinase) pathway is
an early event that contributes to cell proliferation, survival, and tissue invasion …

Biofilms are the dominant bacterial lifestyle. The regulation of the formation and dispersal of
bacterial biofilms has been the subject of study in many organisms. Over the last two …

Background Cystic fibrosis is the most common autosomal recessive genetic disease in
Caucasians. It is caused by mutations in the CFTR gene, leading to poor hydration of mucus …

Rationale: Anaerobic bacteria are present in large numbers in the airways of people with
cystic fibrosis (PWCF). In the gut, anaerobes produce short-chain fatty acids (SCFAs) that …

Until recently, the purpose of studying microbes in pneumonia was the identification of an
organism that could assume the role of “pathogen” in disease. Common findings, using …

BACKGROUND Humans suffer from infections caused by single species or more complex
polymicrobial communities. Identification of infectious bacteria commonly employs …

The modulators of severe COVID-19 have emerged as the most intriguing features of SARS-
CoV-2 pathogenesis. This is especially true as we are encountering variants of concern …